Results 91 to 100 of about 680,317 (306)

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Examining the link between information processing speed and executive functioning in multiple sclerosis [PDF]

, 2009
Slowed information processing speed (IPS) is frequently reported in those with multiple sclerosis (MS), and at least 20% are compromised on some aspect of executive functioning also.
Drew, Margaret A., Margaret A. Drew, Nicola J. Starkey, Robert B. Isler, Starkey, Nicola J., Isler, Robert B.   +5 more
core   +1 more source

INTERRELATION OF THE LOCALIZATION OF FOCI OF DEMYELINATION WITH THE SEVERITY OF COGNITIVE IMPAIRMENT IN PATIENTS WITH MULTIPLE SCLEROSIS

Актуальні проблеми сучасної медицини, 2019
Most investigation of the multiple sclerosis are devoted to the study of motor and sensory disorders. However, patients also are worried about cognitive impairment, which manifests in memory impairment, attention and reduced working capacity.
Djamilya Aravitskaya, Vladimir Dariy
doaj  

[Multiple sclerosis].

Der Radiologe, 2008
Multiple sclerosis is the most common chronic inflammatory disease of myelin with interspersed lesions in the white matter of the central nervous system. Magnetic resonance imaging (MRI) plays a key role in the diagnosis and monitoring of white matter diseases. This article focuses on key findings in multiple sclerosis as detected by MRI.
Grunwald, I, Kühn, A, Backens, M, Shariat, K, Kostopoulos, P, Papanagiotou, P   +5 more
openaire   +3 more sources

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Secondary MRI-findings, volumetric and spectroscopic measurements in mesial temporal sclerosis

Swiss Medical Weekly, 2012
INTRODUCTION: Primary- and secondary MR findings, volumetric measurements and MR spectroscopy data of each hippocampus represent more a dozen of variables that radiologists should consider in a quantitative MR report of temporal lobe epilepsy (TLE).
Maria Luisa Lopez-Acevedo, Manuel Martinez-Lopez, Rafael Favila, Ernesto Roldan-Valadez   +3 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Functioning and disability in multiple sclerosis from the patient perspective [PDF]

, 2011
Multiple sclerosis (MS) has a great impact on functioning and disability. The perspective of those who experience the health problem has to be taken into account to obtain an in-depth understanding of functioning and disability.
Nicolaus König, Michaela Coenen, König, Nicolaus, Alarcos Cieza, Basedow-Rajwich, Birgit, Birgit Basedow-Rajwich, Cieza, Alarcos, Coenen, Michaela, Jürg Kesselring, Kesselring, Jürg   +9 more
core   +1 more source

The Unyielding Enigma

Journal of Indian Academy of Oral Medicine and Radiology
Scleroderma, an autoimmune connective tissue disorder marked by profound fibrosis in visceral organs, skin, and blood vessels, exhibits oral manifestations typically initiating with tongue rigidity and facial skin alterations. It presents with a plethora
Hima John, Jiss Mary, Jeslin James, S Devu   +3 more
doaj   +1 more source