Results 61 to 70 of about 922,760 (302)

Silent progression in disease activity-free relapsing multiple sclerosis. [PDF]

, 2019
ObjectiveRates of worsening and evolution to secondary progressive multiple sclerosis (MS) may be substantially lower in actively treated patients compared to natural history studies from the pretreatment era.
Baranzini, Sergio E, Barba, Patrick, Bevan, Carolyn, Bischof, Antje, Bove, Riley, Caverzasi, Eduardo, Cree, Bruce AC, Gelfand, Jeffrey M, Gomez, Refujia, Goodin, Douglas S, Graves, Jennifer, Green, Ari J, Gundel, Tristan, Hauser, Stephen L, Henry, Roland G, Hollenbach, Jill A, Kirkish, Gina, Oksenberg, Jorge R, Papinutto, Nico, Ragan, Nicholas R, Romeo, Andrew, Rush, Gillian Q, Sacco, Simone, Santaniello, Adam, Stern, William A, University of California, San Francisco MS-EPIC Team, Wilson, Michael R, Zamvil, Scott S, Zhao, Chao, Zhu, Alyssa H   +29 more
core   +1 more source

Systemic sclerosis

The Lancet, 2023
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue disease. Once considered an untreatable and unpredictable condition, research advancements have improved our understanding of its disease pathogenesis and clinical phenotypes and expanded our treatment armamentarium.
Volkmann, Elizabeth R, Andréasson, Kristofer, Smith, Vanessa   +2 more
openaire   +4 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Enfermedad poliquística del hígado Polcystic disease of the liver

Revista Colombiana de Cirugía, 2008
Introducción. La enfermedad poliquística del hígado es una enfermedad de predominio en la mujer, en la cual se encuentran múltiples quistes en el hígado y el riñón que producen síntomas por su crecimiento y efecto de masa. Materiales y métodos.
Héctor René Hazbón
doaj  

Hematopoietic Cell Transplantation for Systemic Sclerosis—A Review

Cells, 2022
Systemic sclerosis (SSc) is an autoimmune, multi-organ, connective tissue disease associated with significant morbidity and mortality. Conventional immunosuppressive therapies demonstrate limited efficacy.
Daniel Levin, Mohammed S. Osman, Caylib Durand, Hyein Kim, Iman Hemmati, Kareem Jamani, Jonathan G. Howlett, Kerri A. Johannson, Jason Weatherald, Matthew Woo, Jason Lee, Jan Storek   +11 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Contribution of irreversible morphological changes of different renal structures to development of anemia in immune glomerulopathies

Терапевтический архив, 2008
Aim. To find out correlations between severity of sclerotic affection of the glomeruli, tubules, interstitium, vessels and development of anemia in patients with glomerulopathy. Material and methods.
V A Dobronravov, V G Sipovskiĭ, I I Trofimenko, A V Dobronravov, I K Klemina, V A Titova, E B Sipovskaia, A V Smirnov   +7 more
doaj  

Tibial deformities caused by focal fibrocartilaginous dysplasia: a narrative review

Frontiers in Pediatrics
Focal fibrocartilaginous dysplasia (FFCD) of the tibia is a rare but well-recognised, “tumour-like” condition that primarily involves the proximal tibia and causes tibial deformities.
Dimitri Fasel, Elio Paris, Victor Aye, Maxime Pilloux, Giacomo De Marco, Oscar Vazquez, Christina Steiger, Romain Dayer, Nathaly Gavira, Dimitri Ceroni   +9 more
doaj   +1 more source

EndoTHeF: Endoluminal Treatment of Hemorrhoids with Foam [PDF]

Iranian Journal of Colorectal Research, 2018
Background: Hemorrhoids are normal anatomical structures, present in individuals from birthandrecognisable even in intrauterinelife. When we talk about haemorrhoids in actual fact we refer to the symptoms caused by haemorrhoids.
Maurizio Ronconi, Silvia Casiraghi, Mattia Schieppati   +2 more
doaj  

Sudden hearing loss as an early detector of multiple sclerosis: a systematic review [PDF]

, 2018
To evaluate whether Sudden Sensorineural Hearing Loss (S-SNHL) may be an early symptom of Multiple Sclerosis (MS). A systematic review was conducted using the following keywords: "Multiple sclerosis, hearing loss, sudden hearing loss, vertigo, tinnitus ...
Bernitsas, E, Di Stadio, A, Dipietro, L, Greco, A, Meneghello, F, Minni, A, Ralli, M, Stabile, M R   +7 more
core   +1 more source