Results 221 to 230 of about 20,344 (273)

Romosozumab-Induced Epidural Calcification in a Hemodialysis Patient. [PDF]

Cureus
Yoshikawa S.
europepmc   +1 more source

Blocking Sphingosine 1-phosphate Metabolism With Fingolimod Prevents the Progression of Vascular Smooth Muscle Cells Calcification in Chronic Kidney Disease. [PDF]

J Cell Physiol
Skafi N, Pelletier S, Soulage CO, Nahle S, Da Cruz BO, Othmani R, Briolay A, Reibel S, Vitale N, Hamade E, Badran B, Magne D, Buchet R, Stockler-Pinto MB, Fouque D, Mebarek S, Brizuela L.   +16 more
europepmc   +1 more source

Osteocytic vinculin controls bone mass by modulating Mef2c-driven sclerostin expression in mice. [PDF]

Bone Res
Wang Y, Huang J, Lin S, Qin L, Hao D, Zhang P, Huo S, Zou X, Chen D, Xiao G.   +9 more
europepmc   +1 more source

A flexible machine learning Mendelian randomization estimator applied to predict the safety and efficacy of sclerostin inhibition. [PDF]

Am J Hum Genet
Legault MA, Hartford J, Arsenault BJ, Yang AY, Pineau J.   +4 more
europepmc   +1 more source

Relationship between bone resorption and sclerostin regulation in apical periodontitis lesions. [PDF]

Odontology
Uysal E, Ersahan S, Ozcelik F, Hepsenoglu YE.   +3 more
europepmc   +1 more source

Effects of anti-osteoporotic drugs in patients with chronic kidney disease: a systemic review and network meta-analysis of bone mineral density, clinical fracture rate and renal function. [PDF]

Front Pharmacol
Wung CH, Liu HY, Tsai TT, Chen JJ.
europepmc   +1 more source

Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice. [PDF]

J Cachexia Sarcopenia Muscle
Zhou B, Hu J, Yu Y, Sun L, Wang Y, Zhang Q, Jiang Y, Wang O, Xing X, Xia W, Wang L, Zhang G, Li M.   +12 more
europepmc   +1 more source

Evaluating Sclerostin as a Biomarker for Bone Health in Hyperthyroidism: A Clinical and Hormonal Correlation Study.

J Pharm Bioallied Sci
Thambidurai I, Prabha SL, Nagar S, Patil H, Ayyappan S, Periasamy P.   +5 more
europepmc   +1 more source

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Sclerostin

Current Opinion in Endocrinology, Diabetes & Obesity, 2014
Discovery of the Wnt signaling pathway and understanding the central role of osteocyte in skeletal homeostasis have been the major advances in skeletal biology over the past decade. Sclerostin, secreted mainly (but not exclusively) by osteocytes, has emerged as a key player in skeletal homeostasis.
Mahalakshmi, Honasoge, Ajay D, Rao, Sudhaker D, Rao   +2 more
openaire   +2 more sources

Sclerostin deficiency in humans

Bone, 2017
Sclerosteosis and van Buchem disease are two rare bone sclerosing dysplasias caused by genetic defects in the synthesis of sclerostin. In this article we review the demographic, clinical, biochemical, radiological, and histological characteristics of patients with sclerosteosis and van Buchem disease that led to a better understanding of the role of ...
Lierop, A.H. van, Appelman-Dijkstra, N.M., Papapoulos, S.E.   +2 more
openaire   +3 more sources