Results 71 to 80 of about 556,394 (331)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
MethodsXEnvironmental and climate policies, as well as the knowledge underpinning them, are often developed in isolation. This is evident in offsetting research and policy, which tend to address carbon, biodiversity, and water as separate issues.
Felice Diekel +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
SCEL scoping exercise: early learning and childcare sector in Scotland [PDF]
, 2015 In 2013, in response to Teaching Scotland's Future (Donaldson, 2010), at the Scottish Learning Festival, The Scottish College for Educational Leadership (SCEL) was launched as an independent body supporting the leadership development of teachers and ...
Wingrave, Mary
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Considerations for conducting a scoping review in pharmacy education
Exploratory Research in Clinical and Social PharmacyInterrogating the literature is among the first steps a researcher undertakes when actuating a research project or also when any scholar might seek to know what has been done in an area, best practices for conducting a certain activity, or simply to seek
Cherie Lucas, Shane P. Desselle
doaj +1 more source
Securing the Livelihoods and Nutritional Needs of Fish-Dependent Communities [PDF]
, 2013 Starting in June 2012, the Rockefeller Foundation began investigating the pressing problem of the declining health of the oceans due to climate change, overfishing, pollution and habitat destruction, and the effects of this decline on poor and vulnerable
Amanda Goldberger +2 more
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Living Arrangement Options for People with Intellectual Disabilities: A Scoping Review [PDF]
, 2014 This is one of a pair of reports prepared for the Moving Ahead Project. Its partner policy review, Mapping the National Intellectual Disability Landscape (Linehan et al., 2014), outlines current disability services, practices and policies in Ireland ...
Craig, Sarah +7 more
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