Results 61 to 70 of about 43,177 (246)

Applications of implementation science frameworks, models and theories in disparities-focused cancer screening interventions: a scoping review protocol

BMJ Open, 2023
Background Implementation science (IS) frameworks, models and theories (FMTs) have gained popularity in guiding the implementation and evaluation of evidence-based interventions (EBIs) for cancer screening. However, there are significant research gaps in
Serena Xiong, Lisa Klesges, Michelle Doering, Rebekah J Pratt   +3 more
doaj   +1 more source

Black Health in Canada: Protocol for a Scoping Review

JMIR Research Protocols, 2023
Background Black Canadians experience poor health care, poor health outcomes, and a greater burden of health inequalities, much of which is rooted in the unequal distribution of social determinants of health.
Adedoyin Olanlesi-Aliu, Dominic Alaazi, Bukola Salami   +2 more
openaire   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Fall prevention interventions for Hispanic/Latino older adults: a scoping review protocol

Frontiers in Public Health
BackgroundDespite the importance of fall prevention among older adults, limited research exists on interventions tailored to rapidly growing Hispanic/Latino populations in the United States.
Janet Lopez, Michael Joseph Dino, Chitra Banarjee, Chitra Banarjee, Ladda Thiamwong   +4 more
doaj   +1 more source

Adult stroke survivor’s reintegration to normal living: a scoping review protocol

Systematic Reviews, 2021
Background To the best of our knowledge, a scoping review of the published literature investigating the determinants of adult stroke survivors’ reintegration to normal living has not been conducted.
Michael Opeoluwa Ogunlana, Pragashnie Govender, Olufemi Oyeleye Oyewole, Ifeoma Blessing Nwosu   +3 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Use of machine learning in occupational risk communication for healthcare workers: protocol for scoping review

BMJ Open
Introduction With the development of technology, the use of machine learning (ML), a branch of computer science that aims to transform computers into decision-making agents through algorithms, has grown exponentially.
Gabriela Laudares Albuquerque de Oliveira, Clarice Alves Bonow, Itiberê de Oliveira Castellano Rodrigues, Amanda Xavier Geraldo   +3 more
doaj   +1 more source

Physician engagement in hospitals: a scoping review protocol [PDF]

BMJ Open, 2018
Introduction Literature on healthcare reforms highlights the importance of physician engagement, suggesting that it is a critical factor for lowering costs while improving efficiency, quality of care, patient safety, physician satisfaction and retention.
Perreira, Tyrone, Perrier, Laure, Prokopy, Melissa, Jonker, Anthony   +3 more
openaire   +2 more sources

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source