Results 131 to 140 of about 52,068 (305)

Residual Effects of Acute and Subchronic Zolpidem Treatments on Attentional Processes in Aged Female Rats

open access: yesFundamental &Clinical Pharmacology, Volume 40, Issue 1, January 2026.
ABSTRACT Rational Zolpidem, a hypnotic Z‐drug commonly prescribed to promote sleep, is predominantly used over the age of 50. In this elderly population, adverse behavioral disturbances, impaired driving performance, and an increased risk of falls have been frequently reported.
Marianne Leger   +7 more
wiley   +1 more source

The effect of Ginkgo biloba extract on scopolamine-induced apoptosis in the hippocampus of rats

open access: yes, 2013
Apoptosis, known as programmed cell death, plays a crucial role in normal development and tissue homeostasis. Apoptosis is also involved in neurodegenerative diseases such as Alzheimer's disease.
Babakordi, F.   +2 more
core   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 1, January 2026.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi   +4 more
wiley   +1 more source

Evaluation of sixteen antimotion sickness drugs under controlled laboratory conditions [PDF]

open access: yes
Evaluation of antimotion sickness drugs under controlled laboratory ...
Graybiel, A., Wood, C. D.
core   +1 more source

Heroin Adulterated with the Novel Synthetic Cannabinoid, 5F-MDMB-PINACA: A Case Series [PDF]

open access: yes, 2020
Introduction: Heroin can be adulterated with various substances that may or may not have pharmacological effects. Here we report a case series of 8 patients who presented to the emergency department after overdose with intravenous heroin preparation ...
Arnold, Ryan   +5 more
core  

Objective Assessment of Visibility of Colorectal Lesions Using Eye Tracking for New Image‐Enhanced Endoscopy Observation

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 1, Page 278-285, January 2026.
ABSTRACT Background and Aim This study aimed to objectively evaluate colorectal lesion visibility using white‐light imaging (WLI), narrow‐band imaging (NBI), and texture and color enhancement imaging (TXI) with an eye tracking system. Methods Twelve endoscopists assessed 120 images of 30 colorectal lesions (29 adenomas, one sessile serrated lesion ...
Aiji Hattori   +17 more
wiley   +1 more source

Ameliorating the effect of Zingiber officinale (ginger) hydroethanolic extract on scopolamine-induced memory impairment in adult male rats [PDF]

open access: yes, 2015
Background and aims: The spice Zingiber officinale or ginger possesses antioxidant and neuroprotective effects. In this study we hypothesized that treatment with hydroethanolic extract of ginger (50, 100 and 200 mg/kg, p.o) would have an effect on the ...
Gomar, A.   +3 more
core  

Clinical Trial: Efficacy and Safety of Velusetrag in Chronic Intestinal Pseudo‐Obstruction: A Randomized, Phase 2, Placebo‐Controlled, Crossover, Multiple (n = 1), Proof‐of‐Concept Study

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 1, January 2026.
This phase 2 proof‐of‐concept trial evaluated the efficacy and safety of velusetrag in patients with chronic intestinal pseudo‐obstruction. Velusetrag treatment was generally well tolerated and was associated with improved symptoms and a reduction in pseudo‐obstructive episodes versus placebo, although these differences did not reach statistical ...
Carolina Malagelada   +9 more
wiley   +1 more source

Transdermal and Powdered Scopolamine-Induced Anisocoria: A Report of Two Cases

open access: yesCase Reports in Ophthalmology
Introduction: In this case report, we present 2 cases of sudden-onset anisocoria caused by accidental exposure to scopolamine in 2 young female patients. Case Presentation: Two patients presented with unilateral anisocoria.
Leyan Li, Lili Lian, Rong Zhou
doaj   +1 more source

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