Network pharmacology, molecular docking and <i>In vivo</i> validation reveal the neuroprotective effects of TT-TeMac™ against cholinergic dysfunction and hippocampal lesions. [PDF]
Ambamba BDA +11 more
europepmc +1 more source
Blood Metabolomic Profiling of Systemic Responses to Dried Black Lychee in a Scopolamine-Induced Cognitive Impairment in Rats. [PDF]
Weerateerangkul P +15 more
europepmc +1 more source
Evaluation of the Neuroprotective Effects of Diospyros discolor and Diospyros ebenum Leaf Bioactive Fractions In Vivo and Their UPLC-ESI-MS/MS Chemical Characterization: A Comparative Study. [PDF]
Fareed N +4 more
europepmc +1 more source
"Behavioral and Neuroinflammatory Evaluation of a Novel Isoxazole-5-One Derivative in Animal Models of Alzheimer's Disease via TNF-α, COX-2, IL-6, and NF-κB Modulation". [PDF]
Gohar N +6 more
europepmc +1 more source
Scopolamine Prevents Dreams during General Anesthesia
BACKGROUND: Dreaming during anesthesia is not a well-understood phenomenon. Anticholinergic drugs are used in anesthesia as premedication, but their use to decrease the incidence of dreams and psychological adverse reactions after anesthesia is not well ...
PEDUTO, Vito, Adelchi T., Pancaro C.
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Behavioral and Biochemical Evaluation of a Curcumin-Loaded Nano-Liposomal Formulation in a Scopolamine-Induced Mouse Model of Cognitive Impairment. [PDF]
Lee HY +5 more
europepmc +1 more source
Scopolamine (hyoscine) for preventing and treating motion sickness
Background: This is an update of a Cochrane Review first published in The Cochrane Library in Issue 3, 2004 and previously updated in 2007. Motion sickness, the discomfort experienced when perceived motion disturbs the organs of balance, may include ...
Spinks, Anneliese +3 more
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Fabrication and efficacy evaluation of scopolamine-loaded dissolving microneedle for rapid antidepressant therapy. [PDF]
Wang Y +11 more
europepmc +1 more source
Development and application of a radioreceptor assay for scopolamine
6 beta,7 beta-Epoxy-3a(1aH,5aH)-tropanyl-(S)-tropate (scopolamine) has proved to be a very effective drug in the prevention of motion sickness, however, the drug has a small therapeutic window, a low bioavailability and a short half-life.
Ensing, K. +5 more
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