Results 91 to 100 of about 24,322 (210)

Persistent Effects of Prenatally Administered Scopolamine

, 1980
Acute effects of anticholinergic drugs on behavior are well documented (Warburton, 1975); however, evidence of chronic effects of these drugs administered prenatally is practically nonexistent.
Linda Ramirez, Michael E. Campbell
core   +1 more source

Determining the Antioxidant Properties of Chamomile and Investigating the ‎Effects of Chamomile Ethanol Extract on Motor Coordination Disorders in Rats ‎

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Alzheimer’s, a progressive disorder causing the memory and other crucial functions of the brain to deteriorate, is mainly responsible for Dementia (brain deterioration).
Z Rabiei, Z Alibabaei, M Rafieian-kopaei
doaj  

Neuroprotection of N-benzylcinnamide on scopolamine-induced cholinergic dysfunction in human SH-SY5Y neuroblastoma cells

Neural Regeneration Research, 2017
Alzheimer's disease, a progressive neurodegenerative disease, affects learning and memory resulting from cholinergic dysfunction. Scopolamine has been employed to induce Alzheimer's disease-like pathology in vivo and in vitro through alteration of ...
Nicha Puangmalai, Wipawan Thangnipon, Rungtip Soi-ampornkul, Nirut Suwanna, Patoomratana Tuchinda, Saksit Nobsathian   +5 more
doaj   +1 more source

Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 11, Page 5588-5596, November 2026.
ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao, Hui‐Xin Meng, Xue‐Jiao Xu, Zeng‐Lin Zhang, Jian‐Feng Zhang, Yong‐Feng Guo, Inhwan Hwang, Shi‐Jian Song   +7 more
wiley   +1 more source

Blockade of conditioned taste aversion by scopolamine and N-methyl scopolamine: associative conditioning, not amnesia.

, 2016
The anticholinergic, scopolamine, consistently disrupts one-trial passive avoidance conditioning but the effects of such drugs on one-trial conditioned taste aversion (CTA) are variable and contradictory.

core   +1 more source

Amitriptyline and scopolamine in an animal model of depression [PDF]

, 1981
Adult male Sprague-Dawley rats were subjected to acute (95 dB white noise) or chronic stress, or their combination. In comparison with unstressed controls, stressed rats were more active upon several measures of open field activity.
Katz, Richard J., Hersh, S.
core   +1 more source

Tonoplast‐Localized ABCC Transporters Enhance Heterologous Production of the Antidiabetic Montbretin A and Its Analogues in Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 11, Page 5991-6006, November 2026.
ABSTRACT The plant‐derived specialized metabolite montbretin A (MbA) is under development as an improved treatment for Type 2 diabetes, a worldwide epidemic. MbA is an acylated flavonol glycoside so far only found in small amounts in montbretia (Crocosmia × crocosmiiflora) corms.
Charlotte Hijmans, Filipe Cabrita Cruz, Lars H. Kruse, Joerg Bohlmann, Sandra Irmisch   +4 more
wiley   +1 more source

Establishing zebrafish as a model to study the anxiolytic effects of scopolamine

, 2017
Scopolamine (hyoscine) is a muscarinic acetylcholine receptor antagonist that has traditionally been used to treat motion sickness in humans. However, studies investigating depressed and bipolar populations have found that scopolamine is also effective ...
Taylor Pitman, Lucas, Kayla, Harris, Megan, Shannon Digweed, Adam Morrill, Joshua Gallup, Gallup, Joshua, Kayla Lucas, Morrill, Adam, Melike Schalomon, Hamilton, Trevor J, Megan Harris, Schalomon, Melike, Trevor J. Hamilton, Healey, Meghan, Digweed, Shannon, Meghan Healey, Martin Tresguerres, Pitman, Taylor, Tresguerres, Martin, Hamilton, Trevor   +20 more
core   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Scopolamine-induced learning impairment reversed by physostigmine in zebrafish.

, 2010
In this study, the effects of scopolamine, an acetylcholine muscarinic receptor antagonist, and physostigmine, an acetylcholinesterase inhibitor, on the learning ability and memory of zebrafish were evaluated using a passive avoidance response test.
Lee, CJ, Kim, D, Kim, YH, Lee, Y, Jung, MW   +4 more
core   +1 more source