Results 71 to 80 of about 23,536 (214)

Scopolamine alleviates involuntary lingual movements: tardive dyskinesia or dystonia?

, 2017
Jianbo Hu,1,2,* Jianbo Lai,1,2,* Shaohua Hu,1,2 Yi Xu1,2 1Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; 2The Key Laboratory of Mental Disorder’s Management in Zhejiang Province ...
Lai JB, Hu SH, Hu JB, Xu Y
core  

A non-aqueous solid phase extraction method for alkaloid enrichment and its application in the determination of hyoscyamine and scopolamine

, 2012
A non-aqueous solid phase extraction (SPE) method utilizing silica based strong cation exchange (SCX) was developed and optimized for the enrichment of alkaloids.
Wang, Chaoran, Zeng, Jing, Nordahl, Lilly, Liang, Xinmiao, Long, Zhen, 梁鑫淼, Guo, Zhimou, Zhang, Xiuli, Zeng, Jianguo, 张秀莉   +9 more
core   +1 more source

Antidepressant and anxiolytic activity of Lavandula officinalis aerial parts hydroalcoholic extract in scopolamine-treated rats

Pharmaceutical Biology, 2017
Context: Anxiety and depression are common in Alzheimer’s disease (AD). Despite some evidence, it is difficult to confirm Lavandula officinalis Chaix ex Vill (Lamiaceae) as an anxiolytic and antidepressant drug. Objective: The effects of L.
Batool Rahmati, Zahra Kiasalari, Mehrdad Roghani, Mohsen Khalili, Fariba Ansari   +4 more
doaj   +1 more source

MQ rescues scopolamine-induced spatial memory deficits.

, 2013
Effect of MQ treatment on spontaneous alternation behavior (A) and MWM (B) in a scopolamine-induced amnesia model in mice. In the T-maze, MQ (7–15 mg/kg , p.o.) was administered 20 min before scopolamine (1 mg/kg, i.p.); in the MWM, MQ (7 and 15 mg/kg, p.
Perrine Busquet (282902), Rosalia Bertorelli (282904), Daniele Piomelli (180759), Andrea Cavalli (102196), Glauco Tarozzo (282905), Maria Laura Bolognesi (102185), Valeria Capurro (282901), Joao Pedro Lopes (282903), Angelo Reggiani (282906)   +8 more
core   +1 more source

Ultrasound-assisted extraction of scopolamine and hyoscyamine from Hyoscyamus niger roots using central compost design

Heliyon
Hyoscyamus niger is an important medicinal plant used in medicine and contains tropane alkaloid compounds such as hyoscyamine and scopolamine. In this study, after the selection of the solvent for extracting hyoscyamine and scopolamine, the central ...
Roghayeh Ahmadpour, Bahram Maleki Zanjani, Ghasem-ali Garoosi, Reza Farjaminezhad, Raheem Haddad   +4 more
doaj   +1 more source

A simple square-wave voltammetric method for the determination of scopolamine in pharmaceuticals using a boron-doped diamond electrode

Química Nova, 2014
A simple procedure is described for the determination of scopolamine by square-wave voltammetry using a cathodically pretreated boron-doped diamond electrode. Cyclic voltammetry studies indicate that the oxidation of scopolamine is irreversible at a peak
Simone Birkheur Santos, Camila Farinha Valezi, Jessica Scremin, Carlos Alberto Rossi Salamanca-Neto, Luiz Henrique Dall'Antonia, Elen Romão Sartori   +5 more
doaj   +1 more source

Time to Confirmed Completion of Bowel Preparation as a Preprocedural Indicator of Colonoscope Insertion Difficulty: A Prospective Observational Study

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aims Runway time, defined as the interval between completion of polyethylene glycol ingestion and the start of colonoscopy, has been studied as a determinant of bowel cleansing quality. However, whether the bowel preparation course itself is associated with colonoscope insertion difficulty remains unclear.
Kazuki Horiuchi, Yusuke Ishibashi, Hiroki Ueda   +2 more
wiley   +1 more source

Nacre extract prevents scopolamine-induced memory deficits in rodents

Asian Pacific Journal of Tropical Medicine, 2018
Objective: To investigate whether the extract from the nacreous layer of pearl oysters (nacre extract) improves impairments in memory caused by scopolamine administration in rodents. Methods: Nacre extract was prepared from the inner shell layer of pearl
Tatsuya Fuji, Tatsurou Inoue, Yasushi Hasegawa   +2 more
doaj   +1 more source

Dualsteric and dual‐acting modulation of muscarinic receptors by antagonist KH‐5

British Journal of Pharmacology, Volume 183, Issue 19, Page 5769-5790, October 2026.
Abstract Background and purpose Muscarinic acetylcholine receptors are key therapeutic targets, and ligands engaging both orthosteric and allosteric sites may offer improved selectivity and efficacy. Here, we investigated whether the muscarinic antagonist KH‐5 acts as a dualsteric antagonist and defined its mode of interaction with muscarinic receptors.
Alena Janoušková‐Randáková, Eva Dolejší, Nikolai Chetverikov, Jan Jakubík   +3 more
wiley   +1 more source

Scopolamine as an Antidepressant: A Systematic Review

, 2013
OBJECTIVES: The cholinergic-adrenergic hypothesis of mania and depression states that depression is characterized by an increase in central cholinergic activity relative to noradrenergic tone.
Jaffe, Robert J, Peselow, Eric D, Novakovic, Vladan   +2 more
core   +1 more source