Results 61 to 70 of about 24,322 (210)

DAU 6215, a novel 5-HT3-receptor antagonist, selectively antagonizes scopolamine-induced deficit in a passive-avoidance task, but not scopolamine-induced hypermotility in rats

, 1993
This study examined the effects of DAU 6215, a selective 5-HT3-receptor antagonist, on either impairment of a passive-avoidance task or hypermotility, both caused by scopolamine in rats. In the first experiment, scopolamine (0·75 mg kg−1, i.p.) disrupted
Nikolaos Pitsikas, Alessandro Brambilla, Aldo Ghiorzi, Franco Borsini   +3 more
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The Effect of Eight Weeks of Combined Training on Serum Levels of Brain-Derived Neurotrophic Factor, Glial Cell-Derived Neurotrophic Factor, and Tumor Necrosis Factor Alpha in Male Wistar Alzheimer\'s Rat [PDF]

Journal of Ardabil University of Medical Sciences
Background: Given the inconsistent findings regarding the effects of exercise on cognitive performance and neurotrophins. The present study aimed to investigate the effect of eight weeks of combined training on serum levels of brain-derived neurotrophic ...
Parinaz Tabibvand, Ameneh Pourrahim, Masomeh Dadkhah, Somayeh Asadolahi   +3 more
doaj  

Cholinergic control of visual categorisation in macaques

Frontiers in Behavioral Neuroscience, 2011
Acetylcholine (ACh) is a neurotransmitter acting via muscarinic and nicotinic receptors that is implicated in several cognitive functions and impairments, such as Alzheimer’s disease. It is believed to especially affect the acquisition of new information,
Nikolaos C. Aggelopoulos, Stefanie eLiebe, Stefanie eLiebe, Nikos K Logothetis, Gregor eRainer, Gregor eRainer   +5 more
doaj   +1 more source

Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu, Julia Y. H. Liu, Yasuhiro Nakagami, Zitong Li, Xiaofei Huang, Man P. Ngan, Dexuan Cui, John A. Rudd   +7 more
wiley   +1 more source

Anterior Drooling Versus Posterior Drooling: A Comparative Analysis

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aims To examine the patient population of a tertiary Interdisciplinary Saliva Control Clinic, describe management pathways and identify patients suitable for primary care. Methods Retrospective single‐centre cohort study in a tertiary hospital reviewing patients referred to the Saliva Control Clinic over a 5‐year period.
Kaitlin Duell, Eric Levi, Will Alexander, David Chong, Monica S. Cooper   +4 more
wiley   +1 more source

Effect of crocin on histological changes of hippocampus and memory impairment induced by scopolamine in male rats

مجله دانشگاه علوم پزشکی گرگان, 2020
Background and Objective: Alzheimer is the most common form of dementia in elderly persons. Oxidative stress is one of the main pathological factors in Alzheimer’s disease.
Hamidreza Sameni, Afsaneh Talebian, Abbas Ali Vafaei, Sam Zarbakhsh, Zahra Yaghoubi, Mohammadreza Aldaghi   +5 more
doaj  

Ameliorating the effect of Zingiber officinale (ginger) hydroethanolic extract on scopolamine-induced memory impairment in adult male rats [PDF]

Advanced Herbal Medicine, 2016
Background and aims: The spice Zingiber officinale or ginger possesses antioxidant and neuroprotective effects. In this study we hypothesized that treatment with hydroethanolic extract of ginger (50, 100 and 200 mg/kg, p.o) would have an effect on the ...
Abdolkarim Hosseini, Ali Gomar, Naser Mirazi, Mojtaba Gomar   +3 more
doaj  

A simple square-wave voltammetric method for the determination of scopolamine in pharmaceuticals using a boron-doped diamond electrode

Química Nova, 2014
A simple procedure is described for the determination of scopolamine by square-wave voltammetry using a cathodically pretreated boron-doped diamond electrode. Cyclic voltammetry studies indicate that the oxidation of scopolamine is irreversible at a peak
Simone Birkheur Santos, Camila Farinha Valezi, Jessica Scremin, Carlos Alberto Rossi Salamanca-Neto, Luiz Henrique Dall'Antonia, Elen Romão Sartori   +5 more
doaj   +1 more source

Is sleep affected after microgravity and hypergravity exposure? A pilot study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is known to be affected in space travel and in residents of the international space station. But little is known about the direct effects of gravity changes on sleep, if other factors, such as sleep conditions, are kept constant. Here, as a first exploration, we investigated sleep before and after exposure to short bouts of microgravity ...
Barbara Le Roy, Aurore Jouvencel, Anika Friedl‐Werner, Ludmila Renel, Youcef Cherchali, Raouf Osseiran, Ernesto Sanz‐Arigita, Jean‐René Cazalets, Etienne Guillaud, Ellemarije Altena   +9 more
wiley   +1 more source

Scopolamine alleviates involuntary lingual movements: tardive dyskinesia or dystonia?

, 2017
Jianbo Hu,1,2,* Jianbo Lai,1,2,* Shaohua Hu,1,2 Yi Xu1,2 1Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; 2The Key Laboratory of Mental Disorder’s Management in Zhejiang Province ...
Lai JB, Hu SH, Hu JB, Xu Y
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