Results 81 to 90 of about 17,592 (189)

MiR‐30a‐5p mediates epileptogenesis in epilepsy models by targeting SOX4 to regulate the Wnt/β‐catenin pathway

Epilepsia Open, Volume 11, Issue 3, Page 983-1002, June 2026.
Abstract Objective The pathogenesis of epilepsy is closely associated with neuronal synaptic plasticity. MicroRNAs (miRNAs) can regulate various biological processes by binding to specific sequences on target genes. This study employs bioinformatics, molecular dynamics, and experimental approaches to investigate the mechanism by which MiR‐30a‐5p treats
Zhenlin Yang, Xu Zhang, Jingjing Guo, Yuanxin Wei, Jinzi Li   +4 more
wiley   +1 more source

Effect of Oleuropein on the Gene Expression of Brain-derived Neurotrophic Factor, Stress Oxidative, and Spatial Memory Impairment Caused by Scopolamine in Male Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021
Background and Objectives: Oleuropein is an important phenolic compound found in olive leaves that has important pharmacological functions in the central nervous system and neuroprotective effects in vitro and in vivo conditions. This study was conducted
Gelavij Mahnoodi, Azam Moshfegh
doaj  

Status Epilepticus Alters the Function of Brain‐Derived Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Epilepsy is a neurological disorder characterised by recurrent spontaneous seizures. Approximately 30% of patients are unable to achieve adequate seizure control with available medications, highlighting the need to better understand disease mechanisms and develop improved treatments.
Samantha L. Reed, Yilin Wang, Yangping Li, Guoku Hu, Jingjing Yang, Bing Yao, Andrew Escayg   +6 more
wiley   +1 more source

Neurophysiological correlates of visually induced motion sickness severity: A scoping review of the impact of experimental settings on EEG spectral power

Journal of Intelligent Medicine, Volume 3, Issue 2, Page 152-168, June 2026.
This review synthesizes EEG findings from 28 VIMS studies across four inducing scenarios (abstract cues, virtual videos, vehicle driving, and game scenes) and two display types (HMD and monitor). While Delta/Theta enhancement consistently reflects sensory conflict, Alpha activity shows context dependency: predominantly increasing during passive viewing
Yanru Bai, Zhipeng Yang, Haoran Jiang, Jiedong Nan, Chunyang Hong, Guangjian Ni   +5 more
wiley   +1 more source

The prognostic role of magnetic resonance enterography at diagnosis in paediatric isolated ileocaecal Crohn's disease

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 6, Page 1451-1457, June 2026.
Abstract Objectives We aimed at identifying magnetic resonance enterography (MRE) predictors of surgical intervention and anti‐tumor necrosis factor alpha (TNF‐α) initiation in a paediatric cohort of patients newly diagnosed with isolated ileocaecal (L1) Crohn's disease (CD).
Saverio Pochesci, Luca Scarallo, Federico Rubera, Arianna Pranzetti, Marco Di Maurizio, Massimo Basile, Paolo Emilio Orlandi, Patrizia Alvisi, Paolo Lionetti   +8 more
wiley   +1 more source

Acceptability of Atropine Eyedrops Administered Sublingually for Sialorrhea Treatment Related to Neurological Conditions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Off‐label use of anticholinergic agents (atropine eye drops) administered sublingually are a first‐line treatment in standard clinical practice in France to treat sialorrhea in patients with neurological conditions. The ability and willingness to using and administering such medication have become key factors to ensure safe and effective ...
Hugues Michelon, Clémence Lefèvre‐Dognin, Julie Paquereau, Raphaëlle Guidoni, Vincent Boudy, Fabrice Ruiz, Thibault Vallet   +6 more
wiley   +1 more source

Prospective comparison of diagnostic accuracy of ultrasound, PET/CT and DW‐MRI for preoperative assessment of pelvic lymph nodes in cervical cancer patients: results of the CANNES trial

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 836-851, June 2026.
ABSTRACT Objective To determine whether ultrasound is non‐inferior to positron‐emission tomography/computed tomography (PET/CT) and diffusion‐weighted magnetic resonance imaging (DW‐MRI) in terms of overall diagnostic accuracy for the preoperative assessment of pelvic lymph‐node status in cervical cancer.
F. Frühauf, D. Fischerová, F. Moro, R. Kocián, V. Ptáčník, M. Wagnerová, L. Lambert, A. C. Testa, N. Bizzarri, R. O. Perez, E. Teodorico, D. Cibula, Collaborators, V. Poonyakanok, C. Culcasi   +14 more
wiley   +1 more source

Transdermal and Powdered Scopolamine-Induced Anisocoria: A Report of Two Cases

Case Reports in Ophthalmology
Introduction: In this case report, we present 2 cases of sudden-onset anisocoria caused by accidental exposure to scopolamine in 2 young female patients. Case Presentation: Two patients presented with unilateral anisocoria.
Leyan Li, Lili Lian, Rong Zhou
doaj   +1 more source

The Effectiveness of Non‐Steroidal Anti‐Inflammatory Drugs for Pain Relief During Outpatient Intrauterine Device Insertion: A Systematic Review and Meta‐Analysis

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 3, June 2026.
ABSTRACT Background Fear of procedural pain is a significant barrier to intrauterine device (IUD) uptake. Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used in IUD insertion for their analgesic and anti‐inflammatory properties; however, evidence for their effectiveness remains inconsistent.
Marita S. Bolic, Jack Ainsworth, Clare Heal, Natalie Drever   +3 more
wiley   +1 more source

TAK-071, a muscarinic M1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram power spectral changes in cynomolgus monkeys.

PLoS ONE, 2019
Activation of the muscarinic M1 receptor is a promising approach to improve cognitive deficits associated with cholinergic dysfunction in Alzheimer's disease, dementia with Lewy bodies, and schizophrenia.
Emi Kurimoto, Masato Nakashima, Haruhide Kimura, Motohisa Suzuki   +3 more
doaj   +1 more source