Residual-Based Sieve Maximum Full Likelihood Estimation for the Proportional Hazards Model. [PDF]
Choi T, Halabi S, Kim H, Wu Y.
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Admission creatinine and outcomes in very elderly critically ill patients: a retrospective cohort study. [PDF]
Klopp A +13 more
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Case Report: Improvement in Swallowing Function Following DLPFC-Targeted Repetitive Transcranial Magnetic Stimulation in a Post-Stroke Patient with Cognitive Impairment. [PDF]
Yeh YH, Sun SH, Wu CC, Lee WK.
europepmc +1 more source
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Performance of the Dutch Pediatric Early Warning Score: a nationwide study in academic, large teaching and general hospital contexts, using real-world data. [PDF]
Stevens J +4 more
europepmc +1 more source
Impact of depression and anxiety on health-related quality of life changes over time within individuals with rheumatoid arthritis or inflammatory bowel disease: A prospective Canadian cohort study. [PDF]
Hitchon CA +9 more
europepmc +1 more source

