Results 261 to 270 of about 1,836,547 (316)

RETRACTION: Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and Upar in Glioma

open access: yesMolecular Oncology, EarlyView.
RETRACTION: S. Gopinath, K. Alapati, R. R. Malla, C. S. Gondi, S. Mohanam, D. H. Dinh, and J. S. Rao, “Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and Upar in Glioma,” Molecular Oncology 5, no. 5 (2011): 426–437, https://doi.org/10.1016/j.molonc.2011.07.004.
wiley   +1 more source

Classification of Current Scoring Functions

Journal of Chemical Information and Modeling, 2015
Scoring functions are a class of computational methods widely applied in structure-based drug design for evaluating protein-ligand interactions. Dozens of scoring functions have been published since the early 1990s. In literature, scoring functions are typically classified as force-field-based, empirical, and knowledge-based. This classification scheme
Jie Liu, Renxiao Wang
openaire   +2 more sources

Scoring Functions for AutoDock

2015
Automated docking allows rapid screening of protein-ligand interactions. A scoring function composed of a force field and linear weights can be used to compute a binding energy from a docked atom configuration. For different force fields or types of molecules, it may be necessary to train a custom scoring function.
Anthony D, Hill, Peter J, Reilly
openaire   +2 more sources

Alignment with Context Dependent Scoring Function

Journal of Computational Biology, 2006
In the paper by Gambin et al. (2002) we introduced the model of contextual alignment of biological sequences. It is an extension of the classical alignment, in which the cost of a substitution depends on the surrounding symbols. Consequently, in this model the cost of transforming one sequence into another depends on the order of editing operations. In
Anna Gambin   +2 more
openaire   +2 more sources

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