Results 61 to 70 of about 1,836,547 (316)

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

An approach for MADM problems with interval-valued intuitionistic fuzzy sets based on nonlinear functions

open access: yesTechnological and Economic Development of Economy, 2016
This paper investigates an approach for multiple attribute decision making (MADM) problems with interval-valued intuitionistic fuzzy numbers (IVIFNs). To do that, the nonlinear score, accuracy and hesitation functions of IVIFNs are developed based on the
Jian Wu, Qingwei Cao, Hui Li
doaj   +1 more source

Optimization of a new score function for the detection of remote homologs [PDF]

open access: yes, 2000
The growth in protein sequence data has placed a premium on ways to infer structure and function of the newly sequenced proteins. One of the most effective ways is to identify a homologous relationship with a protein about which more is known.
Sahu, Sarata C.   +18 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Evaluating Continuous Training Programs Using the Generalized Propensity Score [PDF]

open access: yes
This paper assesses the dynamics of treatment effects arising from variation in the duration of training. We use German administrative data that have the extraordinary feature that the amount of treatment varies continuously from 10 days to 395 days (i.e.
Jochen Kluve   +3 more
core   +2 more sources

NN-Harmonic Mean Aggregation Operators-Based MCGDM Strategy in a Neutrosophic Number Environment

open access: yesAxioms, 2018
A neutrosophic number (a + bI) is a significant mathematical tool to deal with indeterminate and incomplete information which exists generally in real-world problems, where a and bI denote the determinate component and indeterminate component ...
Kalyan Mondal   +3 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Evaluation of Intrusion Detection Systems in Cyber Security using Fuzzy OffLogic and MCDM Approach [PDF]

open access: yesNeutrosophic Sets and Systems
Modern cybersecurity infrastructures rely heavily on Intrusion Detection Systems (IDS) to detect and prevent malicious activities and unauthorized access.
Zhengrui Yang
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

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