Results 111 to 120 of about 4,890,855 (299)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
“Lake Woebegone,” Twenty Years Later
Nonpartisan Education Review, 2006 Twenty years ago, John Cannell developed data on test scores that became known as the “Lake Woebegone effect.” This commentary describes that experience.
John Jacob Cannell, M.D.
doaj
The Interaction among Using Test-Taking Strategies, Level of Language Proficiency, and Test Performance [PDF]
Research in English Language Pedagogy, 2014 This study scrutinized the interaction between linguistic and strategic variables in reading comprehension test performance of Iranian EFL learners. To this end, the interaction among the participants’ reading comprehension test performance, use of test ...
Narjes Ghafournia, Akbar Afghari
doaj
Testing exogeneity under distributional misspecification [PDF]
We propose a general test for exogeneity that is robust against distributional misspecification. The test can also be used to identify other types of misspecifications, such as the presence of a random coefficient.
de Luna, Xavier, Johansson, Per
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
A fast score test for generalized mixture models. [PDF]
Biometrics, 2020 Duan R +5 more
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A robust score test of homogeneity for zero-inflated count data. [PDF]
Stat Methods Med Res, 2020 Hsu WW +4 more
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source