Results 101 to 110 of about 4,890,855 (299)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
John J. Cannell's late 1980's “Lake Wobegon” reports suggested widespread deliberate educator manipulation of norm-referenced standardized test (NRT) administrations and results, resulting in artificial test score gains.
Richard P. Phelps
doaj
Segregation and the Black-White Test Score Gap [PDF]
The mid-1980s witnessed breaks in two important trends related to race and schooling. School segregation, which had been declining, began a period of relative stasis. Black-white test score gaps, which had also been declining, also stagnated.
Jacob Vigdor, Jens Ludwig
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Source of Lake Wobegon (slide show)
John J. Cannell's late 1980's "Lake Wobegon" reports suggested widespread deliberate educator manipulation of norm-referenced standardized test (NRT) administrations and results, resulting in artificial test score gains.
Richard P. Phelps
doaj
The relationship between COPD assessment test (CAT) scores and severity of airflow obstruction in stable COPD patients [PDF]
Background COPD is a major cause of morbidity in smokers. The COPD assessment test (CAT) is a validated test for the evaluation of COPD impact on health status.
صادقیه اهری, سعید +2 more
core
2012-13 Arkansas Test Results [PDF]
In early August, the Arkansas Department of Education (ADE) released the 2012-2013 test score results. The following brief will highlight the results of these tests, compare achievement scores over time, and provide a glimpse of regional achievement ...
Crouch, Michael L., Ritter, Gary W.
core +2 more sources
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Further Comment on "'Lake Woebegone,' Twenty Years Later"
no ...
Richard P. Phelps
doaj

