Diagnostic performance of coronary CT angiography for stenosis detection according to calcium score: systematic review and meta-analysis [PDF]
OBJECTIVES: A systematic review and meta-analysis to assess sensitivity and specificity of coronary CT angiography (CCTA) for significant stenosis at different degrees of coronary calcification.
den Dekker, M.A.M. +9 more
core +1 more source
Prevalence of Two-Syllable Digits Affecting Forward Digit Span Test Score
The word length effect shows a connection between word length and working memory performance. Although the relationship between digit verbal length and digit span has been investigated between languages, it has not been investigated within a language. It
Lars E. Egner +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Implementation of Risk-Stratified Breast Cancer Prevention With a Polygenic Risk Score Test in Clinical Practice. [PDF]
Padrik P +6 more
europepmc +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Understanding the Black-White Test Score Gap in the First Two Years of School [PDF]
In previous research, a substantial gap in test scores between White and Black students persists, even after controlling for a wide range of observable characteristics. Using a newly available data set (Early Childhood Longitudinal Study), we demonstrate
Roland G. Fryer, Jr., Steven D. Levitt
core
Verfahrensdokumentation für PTED Skala: Post-Traumatic Embitterment Disorder Selbstbeurteilungsfragebogen [PDF]
Die PTED Skala als Selbstbeurteilungsbogen beinhaltet 19 Items zur Erfassung der Funktionen von Verbitterungsreaktionen auf negative Lebensereignisse. Der Fragebogen enthält 19 individuelle Aussagen.
Lieberei, B. +3 more
core +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Verfahrensdokumentation für KK-SKALA: Krankheitskonzeptskala [PDF]
Die KK-SKALA als Forschungsinstrument erfasst die kognitiven Annahmen und Überzeugungen von schizophrenen Patienten im Laufe langanhaltender Störungen ihres Gesundheitszustandes.
Wilms, H. U., Linden, M., Nather, J.
core +1 more source

