Results 81 to 90 of about 2,536,246 (313)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Assessing the Impact of Characteristics of the Test, Common-items, and Examinees on the Preservation of Equity Properties in Mixed-format Test Equating [PDF]
, 2014 Preservation of equity properties was examined using four equating methods - IRT True Score, IRT Observed Score, Frequency Estimation, and Chained Equipercentile - in a mixed-format test under a common-item nonequivalent groups (CINEG) design.
Wolf, Raffaela
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Bootstrap correcting the score test [PDF]
The Lagrange multiplier test, or score test, suggested independently by Aitchison and Silvey (1958) and Rao (1948), tests for parametric restrictions. Although the score test is an intuitively appealing and often used procedure, the exact distribution of
Dirk Hoorelbeke
core
Verfahrensdokumentation für MaCS: Mannheimer Craving Scale [PDF]
, 2012 Die MaCS dient der quantitativen Messung von Craving bei unterschiedlichen Einzelsubstanzen, kombiniertem und/oder multiplem Substanzgebrauch. Sie besteht aus 12 Items und vier Zusatzitems.
Mann, K. +3 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Permanent Income and the Black-White Test Score Gap [PDF]
Analysts often examine the black-white test score gap conditional on family income. Typically only a current income measure is available. We argue that the gap conditional on permanent income is of greater interest, and we describe a method for ...
Jesse Rothstein, Nathan Wozny
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
A note on the relationship between the information matrx test and a score test for parameter constancy [PDF]
Information matrix (IM) test (White, 1982) has been used for detecting general model misspecification in the applied econometrics literature. Two of the most commonly used asymptotic covariance matrix estimators (ACMEs) for the IM test are the one that ...
Daisuke Nagakura
core