Results 71 to 80 of about 2,536,246 (313)

A new simple score of chronic cough: cough evaluation test

BMC Pulmonary Medicine, 2020
Background Chronic cough has an important impact on physical, social and psychological aspects. A simple and effective method to assess different aspects of chronic cough severity is required.
Wenzhi Zhan, Liting Zhang, Mei Jiang, Meihua Chen, Xiaoling Yuan, Jianxin Sun, Pusheng Xu, Feng Wu, Chunlai Zhang, Wei Luo, Xiaomei Chen, Hu Li, Kefang Lai   +12 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Homogeneity Test of Ratios of Two Proportions in Stratified Bilateral and Unilateral Data

Mathematics
In paired-organ studies such as ophthalmology, otolaryngology, and rheumatology, etc., various approaches take highly correlated bilateral data into account for homogeneity tests but are less likely to focus on combined bilateral and unilateral data ...
Huipei Wang, Chang-Xing Ma
doaj   +1 more source

THE IMPACT OF EARTHQUAKE ON CHILD TEST SCORE

Journal of Indonesian Economy and Business, 2017
Natural disasters always affect different aspects of individual life. They affect almost every part of life, such as the emotional, economic, physical, social, and environmental aspects. Children are believed to be very vulnerable to disasters.
Eny Sulistyaningrum
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Verfahrensdokumentation für FSQ: Fibromyalgia Survey Questionnaire - deutsche Fassung [PDF]

, 2015
Die aktuellen Kriterien zur Diagnostik des Fibromyalgiesyndroms (FMS) ermöglichen es, einen fibromyalgieformen Beschwerdekomplex im Rahmen wissenschaftlicher Untersuchungen und in der klinischen Routine via Selbstauskunft des Patienten zu erfassen.
Häuser, W.
core   +1 more source

Pattern of chronic urticaria and value of autologous serum skin test in Sohag Province, Upper Egypt

Electronic Physician, 2018
Background: Chronic urticaria (CU) is a debilitating disorder with variable clinical course. It is characterized by hives occurring for at least 6 weeks, and is classified as spontaneous or inducible.
Reham Ezz El-Dawla El-Sharkawy, Wafaa Mohamed Abd-Elmaged, Doaa Anwar Ahmed, Sahar Abo El-Fetoh Abdel-Wahed   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Diagnosis of Non-alcoholic fatty liver disease

Journal of Pathology of Nepal, 2016
Non Alcoholic Fatty Liver Disease is the deposition of fat in liver in absence of excessive of alcohol consumption. Non Alcoholic Fatty Liver Disease ranges from simple steatosis to Nonalcoholic steatohepatitis and cirrhosis.
Geetika K.C.
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source