Results 41 to 50 of about 4,890,855 (299)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Identification and validation the predictive biomarkers based on risk-adjusted control chart in gemcitabine with or without erlotinib for pancreatic cancer therapy

Frontiers in Genetics
BackgroundIn a randomized clinical controlled trial (PA.3) conducted by the Canadian Cancer Trials Group, the effects of gemcitabine combined with the targeted drug erlotinib (GEM-E) versus gemcitabine alone (GEM) on patients with unresectable, locally ...
Aijun Zhao, Dongsheng Tu, Ye He, Liu Liu, Bin Wu, Yixing Ren   +5 more
doaj   +1 more source

Pre-test probability for SARS-Cov-2-related infection score: The PARIS score.

PLoS ONE, 2020
IntroductionIn numerous countries, large population testing is impossible due to the limited availability of RT-PCR kits and CT-scans. This study aimed to determine a pre-test probability score for SARS-CoV-2 infection.MethodsThis multicenter ...
Mickael Tordjman, Ahmed Mekki, Rahul D Mali, Ines Saab, Guillaume Chassagnon, Enora Guillo, Robert Burns, Deborah Eshagh, Sebastien Beaune, Guillaume Madelin, Simon Bessis, Antoine Feydy, Fadila Mihoubi, Benoit Doumenc, Luc Mouthon, Robert-Yves Carlier, Jean-Luc Drapé, Marie-Pierre Revel   +17 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Testing the Reliability of Anchoring Susceptibility Scores

Europe’s Journal of Psychology, 2022
Whereas anchoring is a very robust and well-known effect that refers to the assimilation of numeric estimates toward previously considered numbers, the psychological mechanisms behind it have yet to be fully clarified. Research on theories on how susceptibility to anchoring is related to other personality parameters has not been able to provide ...
Lucia Weber, Lukas Röseler
openaire   +3 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

A Priori Reliability of Tests with Cut Score [PDF]

Psychometrika, 2015
The theoretical probability of misclassification in a mastery test is exactly computed using the raw score probability distribution (in the Rasch model) as a function of the examinee’s latent ability. The resulting misclassification probability curve, together with the latent ability distribution in the group of examinees, completely determines the ...
MAGNANO, Guido, Chiara Tannoia, Chiara Andrà   +2 more
openaire   +4 more sources

Generalized score test of homogeneity for mixed effects models

, 2006
Many important problems in psychology and biomedical studies require testing for overdispersion, correlation and heterogeneity in mixed effects and latent variable models, and score tests are particularly useful for this purpose. But the existing testing
Zhang, Heping, Zhu, Hongtu
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Testing Homogeneity of Proportion Ratios for Stratified Bilateral Correlated Data

Mathematical and Computational Applications
Intraclass correlation in bilateral data has been investigated in recent decades with various statistical methods. In practice, stratifying bilateral data by some control variables will provide more sophisticated statistical results to satisfy different ...
Wanqing Tian, Changxing Ma
doaj   +1 more source