Results 71 to 80 of about 1,186,164 (296)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Bivariate scoring rules: Unifying the characterizations of positional scoring rules and Kemeny's rule

Journal of Economic Theory
In this paper the author studies social preference functions (SPFs) which, given the voters' strict preferences \(R\) over some set of alternatives, compute a non-empty set of winning rankings \(\succ\) over a feasible subset of the alternatives. Two of the most prominent classes of SPFs are positional scoring rules and Kemeny's rule, both of which ...
openaire   +3 more sources

Development of a human-computer collaborative sleep scoring system for polysomnography recordings.

PLoS ONE, 2019
The overnight polysomnographic (PSG) recordings of patients were scored by an expert to diagnose sleep disorders. Visual sleep scoring is a time-consuming and subjective process.
Sheng-Fu Liang, Yu-Hsuan Shih, Peng-Yu Chen, Chih-En Kuo   +3 more
doaj   +1 more source

A predictive tool for an effective use of ¹⁸F-FDG PET in assessing activity of sarcoidosis

BMC Pulmonary Medicine, 2012
Background 18F-FDG PET/CT (PET) is useful in assessing inflammatory activity in sarcoidosis. However, no appropriate indications are available. The aim of this study was to develop a prediction rule that can be used to identify symptomatic sarcoidosis ...
Mostard Rémy LM, Kuijk Sander MJ Van, Verschakelen Johny A, Kroonenburgh Marinus JPG van, Nelemans Patty J, Wijnen Petal AHM, Drent Marjolein   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Asymptotic minimum scoring rule prediction [PDF]

, 2018
Most of the methods nowadays employed in forecast problems are based on scoring rules. There is a divergence function associated to each scoring rule, that can be used as a measure of discrepancy between probability distributions.
Federica Giummolè, Giummole', Federica, Valentina Mameli, Mameli, Valentina, Giummolè, Federica   +4 more
core   +1 more source

Credit Scoring Using Colonial Competitive Rule-based Classifier

International Journal of Information and Communication Technology Research, 2011
Credit scoring is becoming one of the main topics in the banking field. Lending decisions are usually represented as a set of classification tasks in consumer credit markets.
Javad Basiri, Fattaneh Taghiyareh, Mohammad Siami, Mohammad Reza Gholamian   +3 more
doaj  

Physical basis of the ‘magnification rule’ for standardized Immunohistochemical scoring of HER2 in breast and gastric cancer

Diagnostic Pathology, 2018
Background Detection of HER2/neu receptor overexpression and/or amplification is a prerequisite for efficient anti-HER2 treatment of breast and gastric carcinomas.
Andreas H. Scheel, Frédérique Penault-Llorca, Wedad Hanna, Gustavo Baretton, Peter Middel, Judith Burchhardt, Manfred Hofmann, Bharat Jasani, Josef Rüschoff   +8 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Sincere Scoring Rules [PDF]

Approval Voting is shown to be the unique scoring rule that leads strategic voters to sincere behavior of three candidates elections in Poisson Games. However, Approval Voting can lead to insincere behavior in elections with more than three candidates ...
Nunez Matias
core