Results 11 to 20 of about 71,010 (276)

Scorpion venom peptides: Molecular diversity, structural characteristics, and therapeutic use from channelopathies to viral infections and cancers

open access: yesPharmacological Research, 2023
Animal venom is an important evolutionary innovation in nature. As one of the most representative animal venoms, scorpion venom contains an extremely diverse set of bioactive peptides.
Zhiqiang Xia   +4 more
doaj   +2 more sources

Scorpion Species with Smaller Body Sizes and Narrower Chelae Have the Highest Venom Potency

open access: yesToxins, 2022
Scorpionism is a global health concern, with an estimation of over one million annual envenomation cases. Despite this, little is known regarding the drivers of scorpion venom potency.
Alannah Forde   +3 more
doaj   +2 more sources

Scorpion envenomation in Brazil: Current scenario and perspectives for containing an increasing health problem

open access: yesPLoS Neglected Tropical Diseases, 2023
Opportunistic scorpion species can colonize urban environments, establishing high-density communities that enhance the chances of human accidents.
C. Guerra-Duarte   +5 more
semanticscholar   +1 more source

Scorpion Peptides and Ion Channels: An Insightful Review of Mechanisms and Drug Development

open access: yesToxins, 2023
The Buthidae family of scorpions consists of arthropods with significant medical relevance, as their venom contains a diverse range of biomolecules, including neurotoxins that selectively target ion channels in cell membranes.
L. C. Mendes   +4 more
semanticscholar   +1 more source

Scorpion envenomation-associated myocarditis: A systematic review

open access: yesPLoS Neglected Tropical Diseases, 2023
Background Scorpion envenomation is associated with several complications. One of the most serious complications is the cardiac involvement in the form of myocarditis that remains the main reason for mortalities associated with scorpion envenomation. The
Reza Fereidooni   +7 more
semanticscholar   +1 more source

Bioactive peptides from scorpion venoms: therapeutic scaffolds and pharmacological tools.

open access: yesChinese Journal of Natural Medicines, 2023
Evolution and natural selection have endowed animal venoms, including scorpion venoms, with a wide range of pharmacological properties. Consequently, scorpions, their venoms, and/or their body parts have been used since time immemorial in traditional ...
Kamau Peter Muiruri   +4 more
semanticscholar   +1 more source

The Enzymatic Core of Scorpion Venoms

open access: yesToxins, 2022
Enzymes are an integral part of animal venoms. Unlike snakes, in which enzymes play a primary role in envenomation, in scorpions, their function appears to be ancillary in most species.
G. Delgado-Prudencio   +5 more
semanticscholar   +1 more source

SCORPION is a stacking-based ensemble learning framework for accurate prediction of phage virion proteins

open access: yesScientific Reports, 2022
Fast and accurate identification of phage virion proteins (PVPs) would greatly aid facilitation of antibacterial drug discovery and development. Although, several research efforts based on machine learning (ML) methods have been made for in silico ...
Saeed Ahmad   +6 more
semanticscholar   +1 more source

Neurological and Systemic Manifestations of Severe Scorpion Envenomation

open access: yesCureus, 2021
Scorpion envenomation is a life-threatening toxicological emergency and considered as a major public health problem, especially in endemic regions (India, Africa, Latin America); it is generally characterized by low resources and tropical or subtropical ...
D. Godoy   +4 more
semanticscholar   +1 more source

Scorpion species of medical importance in the Brazilian Amazon: a review to identify knowledge gaps

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2021
Scorpionism is a relevant medical condition in Brazil. It is responsible for most accidents involving venomous animals in the country, which leads to severe symptoms that can evolve to death. In recent years, an increase of almost 50% in the incidence of
J. Martins   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy