Results 1 to 10 of about 11,746 (218)

Insect-selective spider toxins targeting voltage-gated sodium channels [PDF]

, 2007
The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate Nav channel gating.
Nicholson, GM
core   +1 more source

Animal suicide: An account worth giving? Commentary on Peña-Guzmán on Animal Suicide [PDF]

, 2018
Peña-Guzmán (2017) argues that empirical evidence and evolutionary theory compel us to treat the phenomenon of suicide as continuous in the animal kingdom.
Mikhalevich, Irina
core  

Antibacterial activity of the venom of Heterometrus xanthopus

, 2012
Heterometrus xanthopus (Scorpion) is one of the most venomous and ancient arthropods. Its venom contains anti-microbial peptides like hadrurin, scorpine, Pandinin 1, and Pandinin 2 that are able to effectively kill multidrug-resistant pathogens.
Ahmed, Umair, Fatima, Anees, Fawad, Sardar Atiq, Khalid, Nauman, Mujaddad-ur-Rehman, Malik   +4 more
core   +1 more source

Non-disulfide-Bridge peptide 5.5 from the Scorpion Hadrurus gertschi Inhibits the growth of mycobacterium abscessus subsp. massiliense [PDF]

, 2017
Multi-drug resistant microorganisms have been a growing concern during the last decades due to their contribution in mortality rates worldwide. Antimicrobial peptides (AMPs) are broad spectrum antimicrobial agents that display potent microbicidal ...
Kipnis, Ana Paula Junqueira, Kipnis, André, Mortari, Márcia Renata, Neves, Rogério Coutinho das, Santos, Bruno de Paula Oliveira, Schwartz, Elisabeth Nogueira Ferroni, Silva, Roosevelt Alves da, Souza, Adolfo Carlos, Trentini, Monalisa Martins   +8 more
core   +1 more source

Characterisation of three alpha-helical antimicrobial peptides from the venom of Scorpio maurus palmatus. [PDF]

, 2016
Scorpion venoms provide a rich source of anti-microbial peptides. Here we characterise three from the venom of Scorpion maurus palmatus. Smp13 is biologically inactive, despite sharing homology with other antimicrobial peptides, probably because it lacks
Abdel-Rahman, Andrews, Bahar, Baumann, Bobone, Calvete, Corzo, Dai, Dempsey, Gajski, Galanth, Glukhov, Hancock, Harrison, Hilliard, Holak, Huang, Jenssen, Jiang, Kaduk, Keith Miller, Kobayashi, Livermore, Ludtke, Matsuzaki, Melo, Moerman, Mohamed A. Abdel-Rahman, Mohamed M. Tawfik, Nelson, Nomura, Nomura, Park, Park, Patrick L. Harrison, Peter N. Strong, Powers, Rodríguez, Rodríguez, Shai, Shin, Sreerama, Teixeira, Torres-Larios, Urban, Whitmore, Yamaguchi, Yeaman, Yonezawa, Zasloff, Zasloff, Zeng, Zhang   +52 more
core   +1 more source

Venomics of the scorpion Tityus ocelote (Scorpiones, Buthidae): Understanding venom evolution in the subgenus Archaeotityus

International Journal of Peptide Research and Therapeutics, 2022
AbstractThe subgenusTityus (Archaeotityus)includes small variegated species considered until recently, a basal group withinTityus, one of the most diverse and medically relevant genera of scorpions in the New World.Archaeotityusspecies are distributed in the humid forests of Lower Central America and the Choco, Guiana Shield, and Amazon regions. Due to
Díaz Oreiro, Cecilia, Chang Castillo, Arturo, Lomonte, Bruno, Bonilla Murillo, Fabián, Víquez, Carlos, Alfaro Chinchilla, Adriana, Triana Ricón, Felipe, Sasa Marín, Mahmood   +7 more
openaire   +2 more sources

Effectiveness of anti scorpion venom for red scorpion envenomation

Indian Pediatrics, 2013
To study the efficacy of anti-scorpion venom plus prazocin.Comparison of clinical features, outcome and duration of stay between children receiving anti-scorpion venom plus prazocin or prazocin alone for management of red scorpion envenomation.Requirement for dopamine and requirement and duration of dobutamine therapy were significantly less in ...
Kait Santosh, Pandurang, Jyoti, Singh, S, Bijesh, H P, Singh   +3 more
openaire   +2 more sources

Determination of the Median Lethal Dose and Electrophoretic Pattern of Hottentotta saulcyi (Scorpiones, Buthidae) Scorpion Venom

Journal of Arthropod-Borne Diseases, 2015
Background: In this study, we investigated the lethal potency, electrophoretic protein pattern and in vivo effects of Hottentotta saulcyi scorpion venom in mice. Methods: Scorpions were collected at night, by using a UV lamp from Mardin Province, Turkey.
ErsenAydın Yağmur, Özcan Özkan, KZafer Karaer   +2 more
doaj  

ScorpDb: A Novel Open-Access Database for Integrative Scorpion Toxinology

Toxins
Scorpion stings are a significant public health concern globally, particularly in tropical and subtropical regions. Scorpion venoms contain a diverse array of bioactive peptides, and different scorpion species around the world typically exhibit varying ...
Masoumeh Baradaran, Fatemeh Salabi, Masoud Mahdavinia, Elaheh Mohammadi, Babak Vazirianzadeh, Ignazio Avella, Seyed Mahdi Kazemi, Tim Lüddecke   +7 more
doaj   +1 more source

Scorpion Venom and Its Different Peptides Aid in Treatment Focusing on Cancer Disease with the Mechanism of Action

Trends in Pharmacy
Animal venoms, especially those from scorpions, have garnered interest for their potential therapeutic uses. Scorpion venom is a complex mixture of bioactive compounds, including neurotoxins, enzymes, enzyme inhibitors, and peptides. These peptides have
Radwa Abdallnasser Amen, Gamal Eldein Fathy Abd-Ellatef   +1 more
doaj   +5 more sources