Results 21 to 30 of about 6,814 (206)

A newly described scorpion species, Leiurus abdullahbayrami (Scorpion: Buthidae), and the lethal potency and in vivo effects of its venom

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2011
Currently, medically significant scorpion species belong to the Buthidae family and are represented by the genera Androctonus, Buthus, Mesobuthus, Hottentotta, Parabuthus, Tityus, Centruroides, Leiurus.
O Ozkan, EA Yagmur, M Ark
doaj   +2 more sources

Transcriptome analysis of the venom gland of the scorpion Scorpiops jendeki: implication for the evolution of the scorpion venom arsenal [PDF]

open access: yesBMC Genomics, 2009
Background The family Euscorpiidae, which covers Europe, Asia, Africa, and America, is one of the most widely distributed scorpion groups. However, no studies have been conducted on the venom of a Euscorpiidae species yet.
Wu Yingliang   +7 more
doaj   +3 more sources

Partial purification of peptides present in the Tityus macrochirus (Buthidae) scorpion venom and preliminary assessment of their cytotoxicity

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
Introduction: Scorpion venom contains peptides with neurotoxic action primarily active on ion channels in the nervous system of insects and mammals. They are also characterized as cytolytic and anticancer, biological characteristics that have not yet ...
Clara Andrea Rincón-Cortés   +2 more
doaj   +3 more sources

Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children

open access: yesCase Reports in Critical Care, 2018
Background. Severe scorpion envenomation can lead to severe neurological manifestations, which are an indicator of the severity of the scorpion sting. The direct action of scorpion venom on the central nervous system can explain partly these neurological
Mabrouk Bahloul   +5 more
doaj   +2 more sources

A Deeper Examination of Thorellius atrox Scorpion Venom Components with Omic Technologies

open access: yesToxins, 2017
This communication reports a further examination of venom gland transcripts and venom composition of the Mexican scorpion Thorellius atrox using RNA-seq and tandem mass spectrometry.
Teresa Romero-Gutierrez   +5 more
doaj   +2 more sources

Unveiling the Diversity and Modifications of Short Peptides in Buthus martensii Scorpion Venom through Liquid Chromatography-High Resolution Mass Spectrometry [PDF]

open access: yesToxins
More recently, short peptides in scorpion venom have received much attention because of their potential for drug discovery. Although various biological effects of these short peptides have been found, their studies have been hindered by the lack of ...
Ling Zeng   +8 more
doaj   +2 more sources

Exon Shuffling and Origin of Scorpion Venom Biodiversity

open access: yesToxins, 2016
Scorpion venom is a complex combinatorial library of peptides and proteins with multiple biological functions. A combination of transcriptomic and proteomic techniques has revealed its enormous molecular diversity, as identified by the presence of a ...
Xueli Wang, Bin Gao, Shunyi Zhu
doaj   +2 more sources

Determination of the Median Lethal Dose and Electrophoretic Pattern of Hottentotta saulcyi (Scorpiones, Buthidae) Scorpion Venom

open access: yesJournal of Arthropod-Borne Diseases, 2015
Background: In this study, we investigated the lethal potency, electrophoretic protein pattern and in vivo effects of Hottentotta saulcyi scorpion venom in mice. Methods: Scorpions were collected at night, by using a UV lamp from Mardin Province, Turkey.
ErsenAydın Yağmur   +2 more
doaj   +1 more source

F2 peptide fraction of Androctonus crassicauda scorpion venom: Inducing M2 to M1 macrophage polarization and inhibiting colon carcinoma cell proliferation and migration [PDF]

open access: yesAvicenna Journal of Phytomedicine
Objective: Colorectal cancer (CRC) is among the deadliest malignancies, often diagnosed at advanced stages, limiting treatment efficacy and necessitating alternative therapeutic approaches.
Noushin Ghadiri   +5 more
doaj   +2 more sources

Scorpion venom peptides: Molecular diversity, structural characteristics, and therapeutic use from channelopathies to viral infections and cancers

open access: yesPharmacological Research, 2023
Animal venom is an important evolutionary innovation in nature. As one of the most representative animal venoms, scorpion venom contains an extremely diverse set of bioactive peptides.
Zhiqiang Xia   +4 more
doaj   +1 more source

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