The Enzymatic Core of Scorpion Venoms [PDF]
Toxins, 2022 Enzymes are an integral part of animal venoms. Unlike snakes, in which enzymes play a primary role in envenomation, in scorpions, their function appears to be ancillary in most species.
Gustavo Delgado-Prudencio +5 more
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Evaluation of the Lethal Potency of Scorpion and Snake Venoms and Comparison between Intraperitoneal and Intravenous Injection Routes [PDF]
Toxins, 2014 Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such stings and bites of venomous animals occur every year worldwide.
Naoual Oukkache +6 more
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MS/MS analysis of four scorpion venoms from Colombia: a descriptive approach [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background: Scorpions are widely known for the neurotoxic effects of their venoms, which contain peptides affecting ionic channels. Although Colombia is recognized for its scorpion diversity, only a few studies are available describing the venom content.
Sebastian Estrada-Gómez +3 more
doaj +2 more sources
A comparison of honeybee and scorpion venoms as anticancer agents against three different cancer cell lines: lung, colon, and breast cancer [PDF]
Frontiers in ToxicologyOwing to the drawbacks and adverse effects associated with conventional cancer therapies, there is growing interest in identifying effective natural alternatives. In this study, the anticancer potential of honeybee and scorpion venoms was evaluated using
Fatma H. Galal +6 more
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Target-Specificity in Scorpions; Comparing Lethality of Scorpion Venoms across Arthropods and Vertebrates [PDF]
Toxins, 2017 Scorpions use their venom in defensive situations as well as for subduing prey. Since some species of scorpion use their venom more in defensive situations than others, this may have led to selection for differences in effectiveness in defensive ...
Arie van der Meijden +4 more
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Antimicrobial Activity Developed by Scorpion Venoms and Its Peptide Component [PDF]
Toxins, 2022 Microbial infections represent a problem of great importance at the public health level, with a high rate of morbidity-mortality worldwide. However, treating the different diseases generated by microorganisms requires a gradual increase in acquired ...
Clara Andrea Rincón-Cortés +3 more
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Immunogenicity of two representative American consensus scorpion neurotoxins from the genera Tityus and Centruroides. [PDF]
PLoS Neglected Tropical DiseasesTwo consensus scorpion toxins derived from venoms of the genera Centruroides (NATx, North America), and Tityus (SATx, South America) were rationally designed and recombinantly expressed in Escherichia coli Origami. Both recombinant proteins were produced
Samuel Cardoso-Arenas +9 more
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An overview of some enzymes from buthid scorpion venoms from Colombia: Centruroides margaritatus, Tityus pachyurus, and Tityus n. sp. aff. metuendus [PDF]
Journal of Venomous Animals and Toxins including Tropical DiseasesBackground: In Colombia, several species of Buthidae scorpions belonging to the genera Centruroides and Tityus coexist, and their stings are considered life-threatening to humans because of their venom neurotoxins.
Leydy Lorena Mendoza-Tobar +5 more
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Oral Acute Toxicity and Genotoxicity of Heteroctenus junceus Scorpion Venom. [PDF]
Vet Med SciThe Heteroctenus junceus scorpion venom is a very popular natural extract used in traditional medicine in Cuba. In clinically relevant experimental settings, scorpion venom does not induce general toxicity or an increase in the frequency of micronucleus formation in erythrocytes.
Díaz-García A +4 more
europepmc +2 more sources
Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents. [PDF]
Biochem Res IntGlioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Santiago LR +5 more
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