Results 31 to 40 of about 4,847 (209)

Scorpion Venom Causes Apoptosis by Increasing Reactive Oxygen Species and Cell Cycle Arrest in MDA-MB-231 and HCT-8 Cancer Cell Lines

open access: yesJournal of Evidence-Based Integrative Medicine, 2018
Objectives. The objective of this study was to examine the effect of scorpion venoms on cancer cell progression, apoptosis, and cell cycle arrest. Scorpion venoms are known to possess numerous bioactive compounds that act against cancer progression by ...
Abdulrahman Khazim Al-Asmari PhD   +2 more
doaj   +1 more source

The envenomation of general physiology throughout the last century. [PDF]

open access: yes, 2017
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
core   +1 more source

Scorpion Toxin, BmP01, Induces Pain by Targeting TRPV1 Channel

open access: yesToxins, 2015
The intense pain induced by scorpion sting is a frequent clinical manifestation. To date, there is no established protocol with significant efficacy to alleviate the pain induced by scorpion envenomation.
Md Abdul Hakim   +6 more
doaj   +1 more source

Scorpion venom peptides: Molecular diversity, structural characteristics, and therapeutic use from channelopathies to viral infections and cancers

open access: yesPharmacological Research, 2023
Animal venom is an important evolutionary innovation in nature. As one of the most representative animal venoms, scorpion venom contains an extremely diverse set of bioactive peptides.
Zhiqiang Xia   +4 more
doaj   +1 more source

A non-lethal method for studying scorpion venom gland transcriptomes, with a review of potentially suitable taxa to which it can be applied.

open access: yesPLoS ONE, 2021
Scorpion venoms are mixtures of proteins, peptides and small molecular compounds with high specificity for ion channels and are therefore considered to be promising candidates in the venoms-to-drugs pipeline.
Freek J Vonk   +8 more
doaj   +2 more sources

Scorpion envenomation in Brazil: an update

open access: yesInfectio, 2021
Accidents caused by scorpions represent a major health problem on planet, both in individual terms and in the public health sphere. Morbid events can occur in different manifestations, and different clinical conditions must be differentiated for adequate
Arthur Fernandes Barbosa Parrela
doaj   +1 more source

Antiviral activity of animal venom peptides and related compounds [PDF]

open access: yes, 2017
Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense.
Mata, Élida Cleyse Gomes da Mata   +3 more
core   +2 more sources

Cross-Reactivity and Neutralization Capacity of Polyspecific Antivenom Produced by Razi Institute against Three Species of Buthidea Family Scorpions [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2019
Background: Scorpion sting is a significant health problem in southern provinces of Iran. Many thousands of people are stung by different species of scorpions annually. More than 60 scorpion species have been reported to be present in Iran. However, Razi
Bahzad Masihipour   +4 more
doaj   +1 more source

Spider neurotoxins targeting voltage-gated sodium channels [PDF]

open access: yes, 2005
The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides, and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate sodium channel gating and/or kinetics.
Little, MJ, Nicholson, GM
core   +1 more source

Insect-selective spider toxins targeting voltage-gated sodium channels [PDF]

open access: yes, 2007
The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate Nav channel gating.
Nicholson, GM
core   +1 more source

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