Results 31 to 40 of about 2,761 (158)

Recombinant expression and antigenicity of two peptide families of neurotoxins from Androctonus sp.

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2022
Background: Scorpion neurotoxins such as those that modify the mammalian voltage-gated sodium ion channels (Nav) are the main responsible for scorpion envenomation. Their neutralization is crucial in the production of antivenoms against scorpion stings.
Samuel Cardoso-Arenas   +7 more
doaj   +1 more source

Scorpion Venom as a Source of Antimicrobial Peptides: Overview of Biomolecule Separation, Analysis and Characterization Methods

open access: yesAntibiotics, 2023
Scorpion venoms have long captivated scientific researchers, primarily due to the potency and specificity of the mechanism of action of their derived components. Among other molecules, these venoms contain highly active compounds, including antimicrobial
Sara Nasr   +7 more
doaj   +1 more source

Scorpion Species with Smaller Body Sizes and Narrower Chelae Have the Highest Venom Potency

open access: yesToxins, 2022
Scorpionism is a global health concern, with an estimation of over one million annual envenomation cases. Despite this, little is known regarding the drivers of scorpion venom potency.
Alannah Forde   +3 more
doaj   +1 more source

Comparative Proteomic Analysis of the Venoms from the Most Dangerous Scorpions in Morocco: Androctonus mauritanicus and Buthus occitanus

open access: yesLife, 2023
Morocco is known to harbor two of the world’s most dangerous scorpion species: the black Androctonus mauritanicus (Am) and the yellow Buthus occitanus (Bo), responsible for 83% and 14% of severe envenomation cases, respectively.
Ines Hilal   +7 more
doaj   +1 more source

CROSS NEUTRALIZATION OF SOME KINDS OF SCORPION VENOMS FROM AFRICA AND SOUTH EAST USING VACSERA POLYVALENT SCORPION ANTISERA [PDF]

open access: yesJournal of the Egyptian Society of Parasitology, 2019
Preparation of scorpion antivenin includes administration of the venom to a suitable animal - mostly horses- and after an appropriate period collecting the specific antibodies from the serum of the inoculated animal.
ABIR ELFIKY   +2 more
doaj   +1 more source

Leishmanicidal activity of the venoms of the Scorpions Brotheas amazonicus and Tityus metuendus [PDF]

open access: yesBrazilian Journal of Biology, 2023
Leishmaniasis is a vector-transmitted zoonosis caused by different species of the genus Leishmania, with a wide clinical spectrum. It is a public health problem aggravated by a series of limitations regarding treatment.
D. B. Pereira   +6 more
doaj   +1 more source

Antimicrobial Peptide Analogs From Scorpions: Modifications and Structure-Activity

open access: yesFrontiers in Molecular Biosciences, 2022
The rapid development of multidrug-resistant pathogens against conventional antibiotics is a global public health problem. The irrational use of antibiotics has promoted therapeutic limitations against different infections, making research of new ...
Bruno Amorim-Carmo   +5 more
doaj   +1 more source

Defensive Venoms: Is Pain Sufficient for Predator Deterrence?

open access: yesToxins, 2020
Pain, though unpleasant, is adaptive in calling an animal’s attention to potential tissue damage. A long list of animals representing diverse taxa possess venom-mediated, pain-inducing bites or stings that work by co-opting the pain-sensing pathways of ...
Crystal N. Niermann   +8 more
doaj   +1 more source

Exploring the Inter- and Intra-Specific Variability of Androctonus Scorpion Venoms

open access: yesBiology and Life Sciences Forum, 2023
Scorpion venom possesses a lethal sting and potential medicinal properties, making it a captivating natural elixir. Our study aimed to unravel the composition of Androctonus scorpionvenoms in Morocco.
Ines Hilal   +5 more
doaj   +1 more source

Scorpion Venom Causes Apoptosis by Increasing Reactive Oxygen Species and Cell Cycle Arrest in MDA-MB-231 and HCT-8 Cancer Cell Lines

open access: yesJournal of Evidence-Based Integrative Medicine, 2018
Objectives. The objective of this study was to examine the effect of scorpion venoms on cancer cell progression, apoptosis, and cell cycle arrest. Scorpion venoms are known to possess numerous bioactive compounds that act against cancer progression by ...
Abdulrahman Khazim Al-Asmari PhD   +2 more
doaj   +1 more source

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