Defensive Venoms: Is Pain Sufficient for Predator Deterrence? [PDF]
Pain, though unpleasant, is adaptive in calling an animal’s attention to potential tissue damage. A long list of animals representing diverse taxa possess venom-mediated, pain-inducing bites or stings that work by co-opting the pain-sensing pathways of ...
Crystal N. Niermann +8 more
doaj +2 more sources
Animal Venom Pharmacological Resources: Exploiting Bioactive Peptides to Target Multi-Drug-Resistant Bacteria. [PDF]
Background The escalating rise of multi–drug‐resistant (MDR) bacterial strains significantly threatens global health, creating a “silent pandemic” prompted by natural selection, gene mutation, and horizontal gene transfer. This crisis is worsened by the deficit in the development of new treatments, necessitating the innovative discovery of new potent ...
Jaber R +5 more
europepmc +2 more sources
Exploring the potential of Brazilian Amazonian scorpion venoms: A comprehensive review of research from 2001 to 2021 [PDF]
The Amazon biome is home to many scorpion species, with around two hundred identified in the region. Of these, forty-eight species have been reported in Brazil so far and six of them are of medical importance: Tityus apiacas, T. metuendus, T. obscurus, T.
Joel Ramanan da Cruz +2 more
doaj +2 more sources
Intraspecific variation in protein pattern of red scorpion (Mesobuthus tamulus, coconsis, pocock) venoms from Western and Southern India [PDF]
Red scorpions Mesobuthus tamulus (Coconsis, Pocock) were obtained from different regions of West and South India (Ratnagiri, Chiplun and Ahmednagar from Maharashtra and Chennai from Tamil Nadu, respectively).
R. V. Badhe +5 more
doaj +2 more sources
Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents. [PDF]
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Santiago LR +5 more
europepmc +2 more sources
Identification and Venom Characterization of Two Scorpions from the State of Chihuahua Mexico: Chihuahuanus coahuliae and Chihuahuanus crassimannus [PDF]
Chihuahua is the largest state in Mexico. The ecosystem of this region is composed of large area of bushes, forests, and grasslands, which allows for a specific diversity of fauna; among them are interesting species of non-lethal scorpions.
Carolina Alvarado-Gonzalez +8 more
doaj +2 more sources
Scorpion venomics: a 2019 overview [PDF]
Introduction: A few scorpions are dangerous to humans. Their medical relevance was the initial driving force for venom research. By classical biochemistry and molecular cloning, several venom peptides and their coding transcripts were characterized, mainly those related to toxins.
Jimena I, Cid-Uribe +4 more
openaire +3 more sources
Scorpion Venom and the Inflammatory Response [PDF]
Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics.
Vera L. Petricevich
doaj +3 more sources
Snapshots of scorpion venomics [PDF]
Scorpions are particularly well adapted to survival in extreme habitats (especially arid and semi-arid environments) and their ability to produce and deliver venoms is an important factor in this success. Scorpion venoms are very complex mixtures of different proteins and peptides.
Mohamed A. Abdel-Rahman +2 more
openaire +2 more sources
Interaction of Human Lymphocyte Scavenger Receptors CD5 and CD6 with Toxins from Naja haje, Androctonus australis and Apis mellifera Venoms [PDF]
Animal venoms induce systemic inflammatory response syndrome through their interaction, inter alia, with pattern recognition receptors (PRRs) of the innate immune system.
Dalila Khemili +9 more
doaj +2 more sources

