Scorpion Venom and the Inflammatory Response [PDF]
Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics.
Vera L. Petricevich
doaj +3 more sources
Immunogenicity of two representative American consensus scorpion neurotoxins from the genera Tityus and Centruroides. [PDF]
Two consensus scorpion toxins derived from venoms of the genera Centruroides (NATx, North America), and Tityus (SATx, South America) were rationally designed and recombinantly expressed in Escherichia coli Origami. Both recombinant proteins were produced
Samuel Cardoso-Arenas +9 more
doaj +2 more sources
Oral Acute Toxicity and Genotoxicity of Heteroctenus junceus Scorpion Venom [PDF]
The Heteroctenus junceus scorpion venom is a very popular natural extract used in traditional medicine in Cuba. In clinically relevant experimental settings, scorpion venom does not induce general toxicity or an increase in the frequency of micronucleus formation in erythrocytes.
Alexis Díaz‐García +4 more
wiley +2 more sources
Animal Venom Pharmacological Resources: Exploiting Bioactive Peptides to Target Multi–Drug‐Resistant Bacteria [PDF]
Background The escalating rise of multi–drug‐resistant (MDR) bacterial strains significantly threatens global health, creating a “silent pandemic” prompted by natural selection, gene mutation, and horizontal gene transfer. This crisis is worsened by the deficit in the development of new treatments, necessitating the innovative discovery of new potent ...
Rima Jaber +6 more
wiley +2 more sources
Exploring the potential of Brazilian Amazonian scorpion venoms: A comprehensive review of research from 2001 to 2021 [PDF]
The Amazon biome is home to many scorpion species, with around two hundred identified in the region. Of these, forty-eight species have been reported in Brazil so far and six of them are of medical importance: Tityus apiacas, T. metuendus, T. obscurus, T.
Joel Ramanan da Cruz +2 more
doaj +2 more sources
Effects of Brazilian scorpion venoms on the central nervous system [PDF]
In Brazil, the scorpion species responsible for most severe incidents belong to the Tityus genus and, among this group, T. serrulatus, T. bahiensis, T. stigmurus and T. obscurus are the most dangerous ones. Other species such as T.
Ana Leonor Abrahão Nencioni +3 more
doaj +2 more sources
Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents [PDF]
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago +6 more
wiley +2 more sources
Properties and Pharmacology of Scorpion Toxins and Their Biotechnological Potential in Agriculture and Medicine [PDF]
Scorpion venoms contain a wide range of toxins that interact with a variety of target molecules (ion channels, receptors and enzymes) associated with synaptic transmission, action potential propagation, cardiac function, hemostasis and other ...
Cháriston André Dal Belo +2 more
doaj +2 more sources
Interaction of Human Lymphocyte Scavenger Receptors CD5 and CD6 with Toxins from Naja haje, Androctonus australis and Apis mellifera Venoms [PDF]
Animal venoms induce systemic inflammatory response syndrome through their interaction, inter alia, with pattern recognition receptors (PRRs) of the innate immune system.
Dalila Khemili +9 more
doaj +2 more sources
Microbiota discovered in scorpion venom [PDF]
Abstract With low nutrient availability and presence of numerous antimicrobial peptides, animal venoms have been traditionally considered to be harsh sterile environments that lack bacteria. Contrary to this assumption, recent studies of animal venom and venom-producing tissues have revealed the presence of diverse ...
Barbara Murdoch +3 more
openaire +4 more sources

