Antimicrobial peptides from scorpion venoms. [PDF]
Toxicon, 2014 The need for new antimicrobial agents is becoming one of the most urgent requirements in modern medicine. The venoms of many different species are rich sources of biologically active components and various therapeutic agents have been characterized including antimicrobial peptides (AMPs).
Harrison PL +3 more
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Scorpion Venom: Detriments and Benefits [PDF]
Biomedicines, 2020 Scorpion venom may cause severe medical complications and untimely death if injected into the human body. Neurotoxins are the main components of scorpion venom that are known to be responsible for the pathological manifestations of envenoming.
Shirin Ahmadi +8 more
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Effects of Brazilian scorpion venoms on the central nervous system [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2018 In Brazil, the scorpion species responsible for most severe incidents belong to the Tityus genus and, among this group, T. serrulatus, T. bahiensis, T. stigmurus and T. obscurus are the most dangerous ones. Other species such as T.
Ana Leonor Abrahão Nencioni +3 more
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Properties and Pharmacology of Scorpion Toxins and Their Biotechnological Potential in Agriculture and Medicine [PDF]
ToxinsScorpion venoms contain a wide range of toxins that interact with a variety of target molecules (ion channels, receptors and enzymes) associated with synaptic transmission, action potential propagation, cardiac function, hemostasis and other ...
Cháriston André Dal Belo +2 more
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Exploring the potential of Brazilian Amazonian scorpion venoms: A comprehensive review of research from 2001 to 2021 [PDF]
Toxicon: XThe Amazon biome is home to many scorpion species, with around two hundred identified in the region. Of these, forty-eight species have been reported in Brazil so far and six of them are of medical importance: Tityus apiacas, T. metuendus, T. obscurus, T.
Joel Ramanan da Cruz +2 more
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Pioneering Comparative Proteomic and Enzymatic Profiling of Amazonian Scorpion Venoms Enables the Isolation of Their First α-Ktx, Metalloprotease, and Phospholipase A2 [PDF]
ToxinsScorpionism is a growing public health concern in Brazil, with the Amazon region presenting the highest mortality rates but remaining understudied, especially regarding local scorpion venoms composition.
Karla C. F. Bordon +9 more
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Scorpion Venom and the Inflammatory Response [PDF]
Mediators of Inflammation, 2010 Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics.
Vera L. Petricevich
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Recombinant expression and antigenicity of two peptide families of neurotoxins from Androctonus sp.
Journal of Venomous Animals and Toxins including Tropical Diseases, 2022 Background: Scorpion neurotoxins such as those that modify the mammalian voltage-gated sodium ion channels (Nav) are the main responsible for scorpion envenomation. Their neutralization is crucial in the production of antivenoms against scorpion stings.
Samuel Cardoso-Arenas +7 more
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Antibiotics, 2023 Scorpion venoms have long captivated scientific researchers, primarily due to the potency and specificity of the mechanism of action of their derived components. Among other molecules, these venoms contain highly active compounds, including antimicrobial
Sara Nasr +7 more
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Scorpion Species with Smaller Body Sizes and Narrower Chelae Have the Highest Venom Potency
Toxins, 2022 Scorpionism is a global health concern, with an estimation of over one million annual envenomation cases. Despite this, little is known regarding the drivers of scorpion venom potency.
Alannah Forde +3 more
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