Results 91 to 100 of about 4,372 (260)
Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
iMetaOmics, EarlyView.The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source
iMeta, EarlyView.Integrated single‐cell RNA sequencing, spectral flow cytometry, immune‐receptor repertoire profiling, and plasma proteomics revealed coordinated peripheral immune remodeling during acute scrub typhus. Patients exhibited expansion of cytotoxic, clonally amplified CD8+ T cells with exhaustion‐associated features, depletion and apoptosis of CD4+ T cells ...
Yijia Guo +13 more
wiley +1 more source
Numerical investigation of scour behavior around complex piers under flood conditions
Frontiers in Built EnvironmentIntroductionLocal scour at bridge piers is a primary cause resulting bridge failure, a risk that is significantly exacerbated under extreme hydrodynamic events such as floods.MethodsThis study presents a numerical investigation of the scour behavior ...
Qiang Qin +6 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim +6 more
wiley +1 more source
Journal of Hospital Medicine, EarlyView.Abstract Background Hospitalized older patients are predominantly sedentary, risking functional decline. Nurses and physical therapists are primarily responsible for mobility but have many competing demands. Objectives To explore clinicians' and patients' perceptions of mobility technicians dedicated to support inpatient ambulation.
Jordan M. Alpert +11 more
wiley +1 more source
Human Capital Robotic Integration and Value Creation for Organizations
Journal of Organizational Behavior, EarlyView.ABSTRACT Due to rapid advancements in artificial intelligence and machine learning, the research conversation has drifted from viewing robots as replacements for humans (i.e., the substitute view) to a view that considers the possible benefits of human–robot collaboration in the workplace (i.e., the complementary view).
Chou‐Yu Tsai +6 more
wiley +1 more source
Bank Failure Mechanism of Peatland Meandering Rivers in the Zoige Basin
工程科学与技术, 2017 :Under the action of lateral scour by near bank flow,bank failure of concave bank of meandering river is the direct drive of bend lateral migration.Field surveys in 2011—2016 suggested that numerous meandering rivers,called peatland meandering river,had ...
胡旭跃, 郭楠, 李志威, 吴新宇
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Journal of Quaternary Science, EarlyView.ABSTRACT The Laurentide Ice Sheet covered vast areas of North America during the Wisconsinan, including the Labrador Shelf, off the coast of eastern Canada. The shelf is characterized by glacial cross‐shelf troughs, which have been considered as predominantly eroded by the last ice advance.
Kai‐Frederik Lenz +9 more
wiley +1 more source
Estimation of Scour Depth at Bridge Piers by Using FASTER Model and Experimental Formulas [PDF]
مهندسی منابع آب, 2017 Bridges are one of the most important river structures. One of the main causes of bridge failure is local scour at bridge piers. Yearly, Many bridges failed around the world because of disregarding hydraulic factors.
Elham Ghanbari Adivi +1 more
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