Results 251 to 260 of about 4,286 (293)

Protocol for plasma membrane enrichment by ultracentrifugation for mass spectrometry of cell lines, xenografts, and patient tumors. [PDF]

STAR Protoc
Hamilton AK, Mooney B, Glisovic-Aplenc T, Radaoui AB, Conkrite KL, De Jong C, Sidoli S, Sorensen PH, Garcia BA, Aplenc R, Maris JM, Morin GB, Diskin SJ.   +12 more
europepmc   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Protocol for establishing primary murine colonic fibroblast culture with induction of loxP/loxP deletion using transducible TAT-Cre recombinase. [PDF]

STAR Protoc
McAninch C, Hahn A, McAninch S, Pinchuk IV, Chulkina M.   +4 more
europepmc   +1 more source

Spectrally accelerated edge and scrape-off layer gyrokinetic turbulence simulations

Baptiste Frei, Philipp Ulbl, Jordy Trilaksono, F. Jenko   +3 more
openalex   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Comparative Analysis of Directional Snare vs Cutting Seton for High Anal Fistula Treatment. [PDF]

Med Sci Monit
Zhong ML, Huang Y, Li XZ, Hu XL, Wu XS, Zuo Z, Han QZ, Yang YH, Yan HY, Lu Y.   +9 more
europepmc   +1 more source

Yield, Physicochemical Properties, and Fatty Acid Profile of Vegetable Oil Extracted From Seed Coats of Strychnos pungens Soler. Fruits Collected in Chikomba, Zimbabwe. [PDF]

J Lipids
Zimudzi C, Zharare GE.
europepmc   +1 more source

An efficient parallelization technique for the coupled problems of fluid, gas and plasma mechanics in the grid environment. [PDF]

Sci Rep
Zinchenko A, Fernandez-Gamiz U, Redchyts D, Gorna O, Bilousova T.   +4 more
europepmc   +1 more source

Synthesis of Triphosphate Nucleoside Prodrugs: γ-ProTriPs. [PDF]

Curr Protoc
Tisnerat C, Pertusati F, Serpi M.
europepmc   +1 more source

Artificial Nervous Systems. [PDF]

Adv Sci (Weinh)
Yang L, Cheng Q, Li Y, Wu N, Xu Z, Xu W.
europepmc   +1 more source