Results 31 to 40 of about 3,423,360 (305)

Kinetic simulations of electron heat flux in the scrape-off layer

Nuclear Materials and Energy, 2017
Parallel electron heat flux qe|| on open field lines is studied with the 1D2V kinetic Vlasov-Fokker-Planck (VFP) code KIPP [15–17]. In order to assess the importance of kinetic effects on the scrape-off layer heat transport in a systematic way, a series ...
M. Zhao, A.V. Chankin, D.P. Coster
doaj   +1 more source

Stochastic and Discrete Time Models of Long-Range Turbulent Transport in the Scrape-Off Layer

, 2004
Volchenkov D, Lima R. Stochastic and Discrete Time Models of Long-Range Turbulent Transport in the Scrape-Off Layer. International Journal of Modern Physics B.
Lima, R., Volchenkov, Dimitry, Volchenkov, D., Lima, Ricardo   +3 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Numerical analysis of the impact of an RF sheath on the Scrape-Off Layer in 2D and 3D turbulence simulations

Nuclear Materials and Energy, 2017
Motivated by Radio Frequency (RF) heating studies, the response of the plasma of tokamaks to the presence of a locally polarized limiter is studied. In a first part, we use the TOKAM3X3D global edge turbulence code to analyse the impact of such biasing ...
P. Tamain, C. Colin, L. Colas, C. Baudoin, G. Ciraolo, R. Futtersack, D. Galassi, Ph Ghendrih, N. Nace, F. Schwander, E. Serre   +10 more
doaj   +1 more source

Nonlocal heat flux application for Scrape-off Layer plasma

, 2017
International audienceThe nonlocal expression proposed by Luciani-Mora-Virmont is implemented into a 1D fluid model for the scrape-off layer. Analytic solutions for heat equation are discussed as well as the impact of sheath boundary conditions on the ...
Ciraolo, Guido, Serre, E., P. Tamain, Ciraolo, G., S. Lepri, Ghendrih, Philippe, Di Cintio, Pierfrancesco, Lepri, S., Tamain, Patrick, Livi, R., Ph. Ghendrih, Y. Marandet, Fedorczak, N, Fedorczak, Nicolas, P. Di Cintio, Serre, Eric, Marandet, Yannick, H. Bufferand, Di Cintio, P, Ghendrih, Ph, Lepri, Stefano, Tamain, P., N. Fedorczak, R. Livi, E. Serre, Bufferand, Hugo, G. Ciraolo, Livi, Roberto, Ghendrih P, Tamain P, Ciraolo G, Serre E, Di Cintio, P., Fedorczak N, Marandet Y, Livi R, Di Cintio P, Lepri S, Bufferand H   +38 more
core   +1 more source

Intermittent fluctuations in the Alcator C-Mod scrape-off layer [PDF]

, 2013
Fluctuations in the boundary region of the Alcator C-Mod tokamak have been analyzed using gas puff imaging data. It is found that the fluctuation amplitudes in the near scrape-off layer follow a normal distribution while the far scrape-off layer ...
LaBombard, Brian, Cziegler, Istvan, Terry, Jim L., Garcia, Odd Erik, Kube, Ralph, Fritzner, Sindre Markus   +5 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Turbulence and transport in spectrally accelerated full-f gyrokinetic simulations

Nuclear Fusion
We investigate edge and scrape-off layer (SOL) turbulence and transport using the spectrally accelerated full- f gyrokinetic (GK) code GENE-X , recently introduced in Frei et al (2025 Comput. Phys. Commun. 316 109817).
B.J. Frei, P. Ulbl, C. Pitzal, W. Zholobenko, F. Jenko   +4 more
doaj   +1 more source