Results 41 to 50 of about 28,655 (296)

Characterisation of the L-mode Scrape Off Layer in MAST: decay lengths

, 2015
This work presents a detailed characterisation of the MAST Scrape Off Layer in L-mode. Scans in line averaged density, plasma current and toroidal magnetic field were performed.
Allan, S., Garzotti, L., Harrison, J., Kirk, A., Lupelli, I., Militello, F., Omotani, J. T., Scannell, R., team, the MAST, Thornton, A. J.   +9 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Numerical analysis of the impact of an RF sheath on the Scrape-Off Layer in 2D and 3D turbulence simulations

Nuclear Materials and Energy, 2017
Motivated by Radio Frequency (RF) heating studies, the response of the plasma of tokamaks to the presence of a locally polarized limiter is studied. In a first part, we use the TOKAM3X3D global edge turbulence code to analyse the impact of such biasing ...
P. Tamain, C. Colin, L. Colas, C. Baudoin, G. Ciraolo, R. Futtersack, D. Galassi, Ph Ghendrih, N. Nace, F. Schwander, E. Serre   +10 more
doaj   +1 more source

Plasma turbulence in the scrape-off layer of the ISTTOK tokamak [PDF]

, 2018
The properties of plasma turbulence in a poloidally limited scrape-off layer (SOL) are addressed, with focus on ISTTOK, a large aspect ratio tokamak with a circular cross section. Theoretical investigations based on the drift-reduced Braginskii equations
Gomes Loureiro, Nuno F, Halpern, Federico D., Jorge, Rogério, Ricci, Paolo, Silva, Carlos   +4 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Turbulence and transport in spectrally accelerated full-f gyrokinetic simulations

Nuclear Fusion
We investigate edge and scrape-off layer (SOL) turbulence and transport using the spectrally accelerated full- f gyrokinetic (GK) code GENE-X , recently introduced in Frei et al (2025 Comput. Phys. Commun. 316 109817).
B.J. Frei, P. Ulbl, C. Pitzal, W. Zholobenko, F. Jenko   +4 more
doaj   +1 more source

Analysis of high-field side plasma instabilities in tokamak edge

Nuclear Materials and Energy
Balanced double-null configurations are of general interest for boundary plasma physics, and they have been proposed for some future designs. Experimental observations demonstrate absence of plasma fluctuations in tokamak high-field side scrape-off layer
M.V. Umansky
doaj   +1 more source

Evolution of filament structures during edge-localized modes in the MAST tokamak [PDF]

, 2006
Edge-localized modes (ELMs) are repetitive instabilities that occur in the outer region of tokamak plasmas. This Letter provides new information on and the implications of the evolution of the filament structures observed during ELMs in the MAST tokamak.
Counsell, G., Dowling, J., Herrmann, A., Kirk, A., Koch, B., Martin, R., MAST Team, Scannell, R., Walsh, M., Wilson, H. R.   +9 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source