Results 41 to 50 of about 578,337 (285)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Able-bodied wild chimpanzees imitate a motor procedure used by a disabled individual to overcome handicap [PDF]

, 2010
Fieldwork of CH was generously supported by grants from the Wenner-Gren Foundation (http://wennergren.org) and the Russell Trust. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Byrne, Richard William, Hobaiter, Catherine   +1 more
core   +1 more source

Scratch na universidade/ Scratch at the university

Brazilian Applied Science Review, 2019
O projeto foi desenvolvido na Universidade Federal de Uberlândia, no Campus Pontal, vinculado ao PROSSIGA-2019. O intuito da ação foi promover uma melhoria no pensamento lógico dos alunos através de uma programação simplificada e interativa (Scratch). Para isso, mediante a divulgação de um curso, foram ministradas aulas durante cinco semanas, focadas ...
Tozzi, Yago Louzada, Vieira, Pedro Henrique, Altomani, Renan Spina, Piovezan, Thaina, Venturini, Patricia Cristina   +4 more
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Educación a distancia. Reto de la superación a través del curso Algoritmización con Scratch

Serie Científica de la Universidad de las Ciencias Informáticas, 2021
Los profesionales de informática y ramas afines reciben actividades de superación a través de la modalidad a distancia. La educación a distancia con el uso de las Tecnologías de la Información y las Comunicaciones (TIC), es una necesidad para la ...
Yor Alex Remond Recio, Rosa María Figueredo Rodríguez   +1 more
doaj  

Ensino de pensamento computacional para alunos do ensino básico usando Computação Desplugada e Scratch

Em Extensão, 2022
A tecnologia está cada vez mais presente no cotidiano das pessoas, portanto, torna- se um importante recurso no processo de ensino e aprendizagem, com possibilidade de adoção não apenas em contextos específicos de cunho tecnológico, mas também em ...
Amanda Karollyne Monteiro Rodrigues, Ana Paula Mundim Silva, Murillo Guimarães Carneiro   +2 more
doaj   +1 more source

Using an interactive whiteboard and a computer-programming tool to support the development of the key competencies in the New Zealand curriculum [PDF]

, 2011
Does children’s use of the software Scratch provide potential for the enhancement of key competencies as they work in pairs at the interactive whiteboard (IWB)?
Forret, Michael, Harlow, Ann, Taylor, Merilyn   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Optimizing intrauterine insemination: A systematic review and meta‐analysis of the effectiveness and safety of clinical treatment add‐ons

Acta Obstetricia et Gynecologica Scandinavica
Introduction Intrauterine insemination (IUI) is one of the most widespread fertility treatments. However, IUI protocols vary significantly amongst fertility clinics. Various add‐on interventions have been proposed to boost success rates. These are mostly
Elpiniki Chronopoulou, Andrea Gaetano‐Gil, Sadaf Shaikh, Claudia Raperport, Bassel H. Al Wattar, Gabriel Ruiz‐Calvo, Javier Zamora, Priya Bhide   +7 more
doaj   +1 more source

Gamification with Scratch or App Inventor in Higher Education: A Systematic Review

Future Internet, 2022
Programming skills should be taught and developed; Scratch and App Inventor are two tools that can contribute significantly to developing this competence in university students.
David Pérez-Jorge, María Carmen Martínez-Murciano   +1 more
doaj   +1 more source