Results 71 to 80 of about 1,914,471 (291)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Erosion Simulation Test of Gravel Pack Metal Mesh Screen Pipe

open access: yesShiyou jixie, 2021
In order to avoid the erosion damage of the metal mesh screen pipe by sand particles in water source well, the post-mixed abrasive jet erosion test device was used to carry out erosion test device installation and test scheme design of gravel pack screen
Zhou Huan, Pang Mingyue
doaj  

A Spherical Actuator-Based Hand-Held Haptic Device for Touch Screen Interaction

open access: yesIEEE Access, 2019
This paper presents a spherical actuator-based hand-held device that provides lateral force feedback for user interaction with the touch screen. The spherical actuator is built around a ball containing the magnetorheological elastomer (MRE).
Dapeng Chen   +4 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

DisConnect: Characterisation of Screen Use and Perception of Health Problems in Students from Aveiro, Portugal – A Cross-Sectional Study

open access: yesPortuguese Journal of Public Health
Introduction: Digitalisation has made technologies an important vehicle for development and learning, especially for children and young people. However, multiple risks of excessive or inappropriate use have been described.
Fábio Sousa Gomes   +5 more
doaj   +1 more source

Screening Devices at School

open access: yesSTS Encounters, 2011
Including children with special needs in the common school has become an international political priority over the past 15-20 years. In reponse, new social technologies have emerged. This article analyses one such technology, an action plan called a SMTTE, and proposes that we understand it as a “screening device”. It is a “device” in the sense that it
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Media Device Use and Vision Disorders in the Pediatric Age: The State of the Art

open access: yesChildren
Introduction. Evidence is consistent with increased screen viewing time among children and adolescents, and anticipation at the age at which children interact with media devices.
Elena Bozzola   +4 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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