Results 61 to 70 of about 2,453,791 (290)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Measuring Excellence in Screen Production Research

, 2018
This document describes how the Australian Screen Production Education and Research Association (ASPERA) recognises, and therefore measures, research quality in screen production.
Berry, Marsha, Kerrigan, Susan, Frankham, Bettina, Batty, Craig, Dooley, Kath, McVeigh, Margaret   +5 more
core   +1 more source

Concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in human milk from Ireland: temporal trends and implications for nursing infant exposure

, 2021
Aim: The elucidation of temporal trends in human exposure to polychlorinated biphenyls (PCBs) and 17 polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) since the previous Irish human milk surveys and to evaluate the impacts of legislative bans and ...
Harrad, Stuart, Keogh, Myra, Cellarius, Claire, Cleere, Kathy, Morrison, John J., Tierney, Julie, Wemken, Nina, Coggins, Marie Ann, Tlustos, Christina, Houlihan, Margarete, O’Riordain, Colman, Noone, Conor, Daly, Sean   +12 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Effects of Screen Time on Early Childhood Development: A Systematic Literature Review

Jurnal Info Kesehatan
The effects of screen time on young children warrant greater attention, particularly as screen use has increased during the COVID-19 pandemic. Excessive screen exposure in early childhood reduces opportunities for adequate stimulation and limits children’
Riama Claudia Christine Lumban Gaol, Nur Alam Fajar   +1 more
doaj   +1 more source

Does Digital Technology Exposure Affect Children's Sleep Duration?

Ankara Medical Journal, 2020
INTRODUCTION: This study aims to investigate the relationship between digital technology screen exposure time and sleep duration in Alpha generation children.
Zeynal Yasacı, Rustem Mustafaoglu
doaj   +1 more source

Associations of excessive screen time and early screen exposure with health-related quality of life and behavioral problems among children attending preschools

BMC Public Health, 2022
Background Both excessive screen time and early screen exposure have been linked to children’s health outcomes, but few studies considered these two exposures simultaneously.
Hongyu Xiang, Li Lin, Weiqing Chen, Chunrong Li, Xinxia Liu, Jinghua Li, Yan Ren, Vivian Yawei Guo   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Study on the relationship between sedentary screen time and dyslipidemia in freshmen of a university in Hubei province [PDF]

Yixue xinzhi zazhi
Objective To explore the relationship between screen-based sedentary time and dyslipidemia among college students, and to provide a basis for the prevention and control of dyslipidemia in adolescents.Methods Newly enrolled college students from a ...
WU Juan, WANG Yan, ZHANG Jin, HE Minghui, HE Wanhong, LUO Yushuang, GU Yihan, ZHENG Chenyang, LIU Yanli, WANG Jing   +9 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source