Results 141 to 150 of about 2,627,927 (334)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Screen Time

Journal of Tropical Pediatrics, 2019
openaire   +3 more sources

Sleep patterns and screen time in US school children during the first 6 months of the COVID-19 pandemic [PDF]

Amanda B. Hassinger, Alberto Monegro, Geovanny F. Pérez   +2 more
openalex   +1 more source

Screen time and associated risks in children and adolescents with autism spectrum disorders during a discrete COVID-19 lockdown period

, 2022
Mathilde Berard, Marianne Périés, Julie Loubersac, Marie‐Christine Picot, Jonathan Y. Bernard, Kerim Münir, Amaria Baghdadli   +6 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

How does screen time affect language development?

Babylonia
Between September and December 2023, Babylonia collected questions from parents regarding their children's language development. This article aims to answer the following questions: I am the mom of a 17 months old.
Ludovica Serratrice
doaj  

Effect of screen time on behavior of pre-schoolers in Islamabad

, 2023
Marriam Suleman, Ume Sughra, Asmaa Riaz, Maheen Akbar   +3 more
openalex   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Effectiveness of a program to lower unwanted media screens among 2–5-year-old children: a randomized controlled trial

Frontiers in Public Health
BackgroundLimited interventions exist on reducing unwanted screen time (ST) among children from low- and middle-income countries (LMICs), so we developed and assessed the effectiveness of the program to lower unwanted media screen time (PLUMS) among ...
Nimran Kaur, Madhu Gupta, Venkatesan Chakrapani, Firoz Khan, Prahbhjot Malhi, Tanvi Kiran, Sandeep Grover   +6 more
doaj   +1 more source