Results 171 to 180 of about 997,787 (297)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

AN INVESTIGATION OF THE RELATIONSHIP BETWEEN 36-72 MONTHLY CHILDREN’S SCREEN TIME AND THEIR BEHAVIORAL PROBLEMS AND EMOTION REGULATION SKILLS: A CASE STUDY IN TURKEY

Turkish International Journal of Special Education and Guidance & Counselling
The amount of time young children spend in front of screens is on the rise and the relationship between the children’s screen time and their social/emotional development is becoming a widely discussed issue.
Hande GÜNGÖR
doaj  

Views of preschool-age children's screen time among mothers with low incomes. [PDF]

J Fam Psychol
Flanagan E, Halpern-Meekin S, Hoiting J, Kerr M, Kirkorian H.   +4 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Screen Time Matters: The Impact of Screen Time on the Risk of Personal-Social Development Outcomes Among Preschool Children in Indonesia: A Cross-Sectional Study. [PDF]

J Multidiscip Healthc
Nurhidayah I, Salsabilla T, Hastuti EA.
europepmc   +1 more source

Screen Time Effects on Pediatrics

, 2019
The purpose of this research is to examine the positive and negative effects of technological screen use by children ages zero to eighteen. The literature reviewed for this research covered the following topics; screen time effects on children ages zero ...
McCracken, Lindsay Michelle
core  

Impact of Screen Time on Physical Activity and Eating Habits: A Case Study of Promoting Healthier Lifestyles in a School of Dhaka, Bangladesh

This research looks for the effects of screen time on physical activity and eating behavior among primary school children in a school located in Dhaka City. The significance of the research lies in the increasing concerns regarding the effect that screen
Khan Md. Hasanuzzaman, Khondokar Sabera Hamid   +1 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Reducing Screen Time for Children [PDF]

Archives of Pediatrics & Adolescent Medicine, 2011
Megan A, Moreno, Fred, Furtner, Frederick P, Rivara   +2 more
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source