Results 191 to 200 of about 2,642,234 (338)
Are play and screen time associated with British preschoolers’ mental health? Cross-sectional findings from the British Preschool Children’s Play Survey [PDF]
Kathryn R. Hesketh, Helen F. Dodd
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Reducing Screen Time for Children [PDF]
Archives of Pediatrics & Adolescent Medicine, 2011 Megan A, Moreno +2 more
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Investigation of Phosphor Screens for Real-time Tuning of Large-area Ion Beam Profile
, 2017 庸介 百合 +5 more
openalex +1 more source
Screen time and crime: the crime substitution hypothesis revisited [PDF]
, 2015 Griffiths, MD, Sutton, M
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The Effects of Family-Based Programs on Preschool Children's Screen Time: A Systematic Review. [PDF]
Children (Basel)Arizmendi Sueiro I, Rico-González M.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source