Results 61 to 70 of about 997,787 (297)

Effects of Screen Time on Preschool Health and Development

open access: yes, 2019
Executive summary The rapid proliferation of personal technology has provided our children with unprecedented access to screen-based devices for both educational and entertainment purposes.
Stewart, T   +4 more
core   +1 more source

From Screen Time to Daily Rhythms

open access: yesJournal of Quantitative Description: Digital Media
Understanding typical smartphone behavior increasingly relies on device-enabled fine-grained data sources that go beyond retrospective self-reports. This study contributes to this knowledge by studying how, when, and under what conditions people engage ...
Roland Toth, Douglas Parry, Martin Emmer
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impact of Mobile Display Technology and Settings on Reaction Time in Young Adults: A Cross Sectional Observational Study

open access: yesNational Board of Examinations Journal of Medical Sciences
Background: The continuous and increased exposure to mobile screen increases the concern about its effects on cognitive functions, particularly reaction time which serves as a sensitive indicator of sensorimotor integration and processing speed.
Franc Oumanath   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Effects of Screen Time on Early Childhood Development: A Systematic Literature Review

open access: yesJurnal Info Kesehatan
The effects of screen time on young children warrant greater attention, particularly as screen use has increased during the COVID-19 pandemic. Excessive screen exposure in early childhood reduces opportunities for adequate stimulation and limits children’
Riama Claudia Christine Lumban Gaol   +1 more
doaj   +1 more source

Anisotropic time-dependant behaviour of the aortic valve

open access: yes, 2011
The complex tri-layered structure of the aortic valve (AV) results in anisotropic quasi–static mechanical behaviour. However, its influence on AV viscoelasticity remains poorly understood.
Bader , Dan L.   +8 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Screen time as an index of family distress

open access: yesCurrent Research in Behavioral Sciences, 2021
The increase in children’s screen time over the last few decades has concerned parents, educators, and policymakers alike, due to its association with negative developmental outcomes.
Joshua K. Hartshorne   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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