Results 71 to 80 of about 15,735,897 (251)

Smartphone screen time reduction improves mental health: a randomized controlled trial

BMC Medicine
Background Smartphone screen time has risen sharply in recent years. Even though an association between smartphone use and mental health is well documented, it is still unclear whether this is simply a correlation or causality.
Christoph Pieh, Elke Humer, Andreas Hoenigl, Julia Schwab, Doris Mayerhofer, Rachel Dale, Katja Haider   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Immersive sound workshop for Screen South [PDF]

"Learn how to create and exhibit an immersive soundscape with access to Screen South’s Digital Hub, complete with studio space and XR sound facilities to capture foley, narrative, interviews, music, and more.
Masumi, M.
core  

Dampak Screen Time terhadap Perkembangan Sosioemosional Anak

Sari Pediatri
Latar belakang. Peningkatan penggunaan perangkat digital pada anak dalam beberapa tahun terakhir telah menimbulkan kekhawatiran akan dampaknya pada perkembangan sosioemosional. Masa kanak-kanak merupakan periode kritis dalam pembentukan kemampuan sosial,
Yunita Astari Karambe, Simplicia Maria Anggrahini, Samuel Willem Nalley   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Association Between Screen Time and Outdoor Time on Adolescent Mental Health and Academic Performance: Evidence from Rural China

Risk Management and Healthcare Policy, 2023
Huan Wang,1 Cody Abbey,1 Thomas Kennedy,1 Erik Feng,1 Robin Li,1 Finley Liu,1 Annli Zhu,1 Sharon Shen,1 Prateek Wadhavkar,1 Scott Rozelle,1 Manpreet K Singh2 1Stanford Center on China’s Economy and Institutions, Stanford University, Stanford, CA, USA ...
Wang H, Abbey C, Kennedy T, Feng E, Li R, Liu F, Zhu A, Shen S, Wadhavkar P, Rozelle S, Singh MK   +10 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Screen time and physical activity in schoolchildren

Cogent Education
The rural world is not exempt from sedentary lifestyles and the globalization of screen use. The aim of this study was to describe the level of physical activity, sedentary time and screen use of schoolchildren, analyzing the existence of differences ...
Sebastián Feu, Juan M. García-Ceberino, Manuel López-de la Cruz, Magdalena López-Pérez   +3 more
doaj   +1 more source