Results 171 to 180 of about 7,150,903 (384)

Prognostische Validität mathematischer Screenings

, 2014
Berthold Gomm
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Screening the Milieu of an abattoir for Bacteria of Public health importance in Makurdi, Benue State, Nigeria

, 2017
Nseabasi Maina N, E. G Vinkings, Ini Ubi Bassey, Augustine A. Unimke, L.O Abulawor   +4 more
openalex   +1 more source

A Gold Nanoparticle—Based Approach for Screening Triplex DNA Binders*

, 2020
Min Han, Abigail K. R. Lytton‐Jean, Chad A. Mirkin   +2 more
openalex   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

Science, 2014
Ophir Shalem, Neville E. Sanjana, E. Hartenian, Xi Shi, David A. Scott, T. Mikkelsen, D. Heckl, B. Ebert, D. Root, John G Doench, Feng Zhang   +10 more
semanticscholar   +1 more source

Computational Search for Magnetic and Non-magnetic 2D Topological Materials using Unified Spin-orbit Spillage Screening

, 2020
Kamal Choudhary
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development

Cell Death and Disease
Ovarian cancer (OV) poses a significant challenge in clinical settings due to its difficulty in early diagnosis and treatment resistance. FOXP4, belonging to the FOXP subfamily, plays a pivotal role in various biological processes including cancer, cell ...
Jing Ji, Qilan Qian, Wenhao Cheng, Xiaoqing Ye, Aixin Jing, Shaojie Ma, Yuanyuan Ding, Xinhui Ma, Yasong Wang, Qian Sun, Xiujun Wang, Yulu Chen, Lan Zhu, Qing Yuan, Menghan Xu, Jingting Qin, Lin Ma, Jiayan Yang, Meiqi Zhang, Ting Geng, Sen Wang, Dan Wang, Yizhuo Song, Boyu Zhang, Yuting Xu, Linyu Xu, Shunfang Liu, Wei Liu, Bin Liu   +28 more
doaj   +1 more source

Ovarian cancer screening

, 2001
Barnaby Rufford, Usha Menon, Ian Jacobs
openalex   +1 more source