Results 91 to 100 of about 33,818 (263)

Clinical Effect and Cost-Effectiveness of Screening for Asymptomatic Carotid Stenosis: A Markov Model

, 2018
Objectives:   Screening for asymptomatic carotid artery stenosis (ACAS) is controversial. The cost-effectiveness of screening depends on screening cost, ACAS prevalence, and the potential stroke reducing effect of best medical treatment (BMT). The aim of
Dominika Högberg, Svensjö, Sverker,, Sverker Svensjö, Wanhainen, Anders,, Anders Wanhainen, Kevin Mani, Högberg, Dominika,, Mani, Kevin,   +7 more
core   +1 more source

The efficiency of screening for carriers of severe thalassemia in three community hospitals in Nakhon Si Thammarat province, Thailand

Journal of Health Science and Medical Research (JHSMR), 2009
Screening methods for thalassemia carriers which have been widely used in Thailand include the Osmotic Fragility Test (OFT) and Dichlorophenol-indophenol precipitation test (DCIP).
S Panyasai, S Cheechang
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Machine Learning-Assisted Screening in Systematic Reviews: A Case Study on Pelvic Inflammatory Disease Prevention

Applied Sciences
This study evaluates ASReview, an open-source machine learning application for study selection in systematic literature reviews, using data from a review of whether screening for sexually transmitted infections reduces the incidence of pelvic ...
Martín Daniel Guadarrama-Atrizco, Francisco Javier Prado-Galbarro, Carlos Sánchez-Piedra, Rosa del Carmen Milán-Segovia, Karina Sánchez-Herrera, Juan Manuel Martínez-Núñez   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Optimal timing of a colonoscopy screening schedule depends on adenoma detection, adenoma risk, adherence to screening and the screening objective: A microsimulation study. [PDF]

Colonoscopy-based screening provides protection against colorectal cancer (CRC), but the optimal starting age and time intervals of screening colonoscopies are unknown.
Misselwitz, Benjamin, Cheng, Chih-Yuan, Beerenwinkel, Niko; id_orcid, Zaika, Viktor, Sonnenberg, Amnon, Beerenwinkel, Niko, Prakash, Meher K, Schlander, Michael, Prakash, Meher K., Lang, Brian M., Poleszczuk, Jan, Lang, Brian M, Krupka, Niklas   +12 more
core   +1 more source

Efficient Variable Screening for Multivariate Analysis

Journal of Multivariate Analysis, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

High-throughput multiplexed T-cell-receptor excision circle quantitative PCR assay with internal controls for detection of severe combined immunodeficiency in population-based newborn screening

, 2012
BACKGROUND: Real-time quantitative PCR (qPCR) targeting a specific marker of functional T cells, the T-cell-receptor excision circle (TREC), detects the absence of functional T cells and has a demonstrated clinical validity for detecting severe combined ...
Pass, Kenneth A., Pai, Sung-Yun, Navas, Jennifer S., Wilkey, Jonathan F., Baptiste, Jennifer C., Comeau, Anne Marie, Gerstel-Thompson, Jacalyn L., Eaton, Roger B.   +7 more
core   +1 more source

A Novel Scale for Diagnosis of Pulmonary Ground‐Glass Nodules: A Multicenter and Ambispective Cohort Study

The Clinical Respiratory Journal
Background A screening tool was devised to aid the diagnosis and treatment of ground‐glass nodules (GGNs). Methods The current ambispective cohort study included retrospective collation of 20 variables synthesizing a patient's clinical characteristics ...
Minhao Yu, Yalin Cheng, Tao Wen, Liming Zhang, Xiubo Wei, Yonghong Wang, Jiang Du, GuangKe Xie, Lei Bi   +8 more
doaj   +1 more source