Results 81 to 90 of about 33,818 (263)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Managers and efficiency in banking [PDF]

This paper presents evidence on the impact of managers on cost efficiency in banking. Stochastic frontier analysis is applied to a unique Finnish data set. The paper finds that manager age and education have strong yet complicated effects.
Kauko, Karlo
core  

Syphilis test availability and uptake at medical facilities in southern China. [PDF]

, 2011
OBJECTIVE: To examine syphilis testing capacity, screening coverage rates and types of syphilis tests used in medical facilities in southern China. METHODS: Eleven of the 14 municipalities in Guangdong province participated.
Joseph Tucker, Li-Gang Yang, Xiang-Sheng Chen, Shen, Song-Ying, Song-Ying Shen, Bin Yang, Chen, Xiang-Sheng, Joseph D Tucker, Tucker, Joseph D, Rosanna Peeling, Cheng Wang, Peeling, Rosanna, Yang, Li-Gang, Wang, Cheng, Yang, Bin   +14 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Text mining for screening efficiency? Testing within a Cochrane public health review

, 2014
Background\ud \ud The requirement for dual screening of titles and abstracts to select papers to examine in full text can\ud create a huge workload, not least when the topic is complex and a broad search strategy is required,\ud resulting in a large ...
Baker, Philip, Thomas, James, O'Mara-Eves, Alison, Lovie-Toon, Yolanda, Weightman, Alison, Francis, Daniel   +5 more
core  

Screening two biodegradable polymers in enhanced efficiency fertiliser formulations reveals the need to prioritise performance goals

, 2022
Enhanced efficiency fertilisers (EEF) may reduce nitrogen (N) losses and improve uptake efficiency through synchronising N release with in-season plant requirements.
Pratt, S., Lobsey, C. R., Lobsey, C.R., Redding, M.R., Robinson, N., Phillips, I., Redding, Matthew R., Schmidt, S., Mayer, David G., Hunter, B., Laycock, B., Witt, T., Mayer, D.G., Phillips, Ian R.   +13 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Tracking updates in clinical databases increases efficiency for variant reanalysis

Genetics in Medicine Open
Purpose: Variant interpretation, guided by American College of Medical Genetics and Genomics guidelines, can inform clinical decision-making. However, interpretations may change over time for a variety of reasons.
Lele Li, Xia Tian, Vaughan Woodzell, Richard A. Gibbs, Bo Yuan, Eric Venner   +5 more
doaj   +1 more source

Rapid Generation of Barley Mutant Lines With High Nitrogen Uptake Efficiency by Microspore Mutagenesis and Field Screening

Frontiers in Plant Science, 2018
In vitro mutagenesis via isolated microspore culture provides an efficient way to produce numerous double haploid (DH) lines with mutation introduction and homozygosity stabilization, which can be used for screening directly.
Runhong Gao, Runhong Gao, Runhong Gao, Guimei Guo, Guimei Guo, Chunyan Fang, Chunyan Fang, Saihua Huang, Saihua Huang, Jianmin Chen, Ruiju Lu, Ruiju Lu, Jianhua Huang, Jianhua Huang, Xiaorong Fan, Chenghong Liu, Chenghong Liu   +16 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source