Results 61 to 70 of about 33,818 (263)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Views of health professionals on risk-based breast cancer screening and its implementation in the Spanish National Health System: A qualitative discussion group study.

open access: yesPLoS ONE, 2022
BackgroundWith the aim of increasing benefits and decreasing harms, risk-based breast cancer screening has been proposed as an alternative to age-based screening.
Celmira Laza-Vásquez   +7 more
doaj   +1 more source

Increasing Efficiency In Airport Security Screening [PDF]

open access: yesWIT Transactions on The Built Environment, 2005
The prominence of aviation security has increased dramatically in recent years. As a reaction to the new threat situation large investments into modern security technology have been made. State-of-the-art X-ray screening equipment provides high resolution images, many image enhancement features and even automatic explosive detection.
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Efficiency of CCHD screening in Taipei.

open access: yes, 2016
Efficiency of CCHD screening in Taipei.
Jia-Kan Chang (2610064)   +12 more
core   +1 more source

A pragmatic assessment of the relative efficiency of outreach chlamydia screening events conducted in non-clinical settings

open access: yesBMC Public Health, 2012
Background Opportunistic screening for chlamydia in non-clinical settings is becoming more common, but little is known about which settings (or events) offer the best return on investment.
Bowden Francis J   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Efficient Screening Method for Antifouling Substances

open access: yesBioscience, Biotechnology, and Biochemistry, 1993
We developed three new assay methods: an antialgal test using the diatoms, Nitzschia closterium and Naviculla sp.; a growth-inhibition assay against invertebrate larvae of Musculista senhousia; and an assessment of the residual amount of tested samples on conventional submerged assay plates used for screening antifouling substances.
Watanabe, Naoharu   +7 more
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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