Results 81 to 90 of about 18,538,278 (363)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Seroprevalence of HIV, HBV, HCV & RPR among cornea donor in the regional institute of ophthalmology
Journal of Integrated Health Sciences, 2017 Introduction: Donor corneas obtained by eye banks are steadily increasing all over the world. Proper evaluation of donor cornea is critical to the success of cornea transplantation.
M H Patel, A M Patel, A M Shah
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
British medical journal, 2018 Objective To investigate the efficacy and safety of prostate-specific antigen (PSA) testing to screen for prostate cancer. Design Systematic review and meta-analysis.
D. Ilić +7 more
semanticscholar +1 more source
Advances in Laboratory MedicineThe determination of urinary albumin, crucial for chronic kidney disease (CKD) diagnosis and monitoring, typically employs quantitative techniques as the gold standard.
Liébanas García Paula +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Screening: Testing times [PDF]
Nature, 2012 Pap tests have been a mainstay of cervical cancer screening, but new tests, vaccines and knowledge might be changing that, including when and how frequently to test.
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A pilot telephone intervention to increase uptake of breast cancer screening in socially deprived areas in Scotland (TELBRECS):study protocol for a randomised controlled trial [PDF]
, 2014 Background: Breast cancer accounts for almost 30% of all cancers and is the second leading cause of cancer deaths in women in Scotland. Screening is key to early detection.
Cavanagh, Julie +7 more
core +1 more source
Frontiers in ImmunologyBackgroundHemophagocytic lymphohistiocytosis can be classified as primary HLH (pHLH) and secondary HLH. The early identify of pHLH can facilitate successful treatment. The rapid screening test greatly facilitated the diagnostic process of pHLH.
Wenshuai Zheng +9 more
doaj +1 more source