Results 51 to 60 of about 684,789 (267)
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Information Services and Use, 2018 The global Open Access movement has undertaken a proposal to ‘flip’ from the traditional subscription model to an open access model. With so many stakeholders involved, such a transition must appeal to the interests of researchers, librarians, funders, and publishers.
openaire +2 more sources
Женщина во фрейме-сценарии русских паремий
Studia Rossica Posnaniensia, 2019 The paper analyses the image of woman in the interpretative frame of Russian paremias. The author asks a number of questions: What role does the woman play in society and family? How is she treated by her husband? How do they treat their children? Who is
Joanna Olechno-Wasiluk
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
If the script doesn’t work, change the script
Education Review, 2022 Every career is different, emerging from different circumstances and almost always influenced by unforeseen opportunities and challenges. The script we write will be revised and edited many times. I have found my script changing at important junctures in my career.
openaire +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Predicting Nielsen Ratings from Pilot Episodes Scripts: A Content Analytical Approach
Series. International journal of tv serial narratives, 2019 Textual and content data were extracted from the pilot episode scripts of 183 new, dramatic television series and used to predict the 18-49 demo ratings for the first five episodes of each series’ first season.
Starling Hunter
doaj +1 more source