Results 11 to 20 of about 358 (89)

How Neuromorphic Microstructures Control In Vitro Early-Stage Neuronal Outgrowth. [PDF]

Adv Sci (Weinh)
Biomimetic approach to neuronal interaction with neuromorphic microstructures. ABSTRACT Neuromorphic biomaterials represent a novel class of materials designed to replicate the architecture and functionality of neuronal structures, offering new opportunities in tissue engineering and bioelectronics.
Latte Bovio C, Matamoros E, Mollo V, Mariano A, Criscuolo V, Santoro F.   +5 more
europepmc   +2 more sources

SCO-ph: Microfluidic Dynamic Phenotyping Platform for High-Throughput Screening of Single Cell Acidification. [PDF]

Small
Single‐cell studies are on the rise; however, dynamic phenotyping studies remain challenging due to the lack of technologies. Single‐cell optical pH analysis (SCO‐pH) offers a high‐throughput, quantitative, and automated extracellular pH analysis platform based on microfluidic technologies.
Jeong H, Leyes Porello EA, Rosario JG, Kuang D, Han SH, Sul JY, Lim B, Lee D, Kim J.   +8 more
europepmc   +2 more sources

Microbiome Single Cell Atlases Generated with a Commercial Instrument. [PDF]

Adv Sci (Weinh)
Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Li X, Xu L, Demaree B, Noecker C, Bisanz JE, Weisgerber DW, Modavi C, Turnbaugh PJ, Abate AR.   +8 more
europepmc   +2 more sources

Model‐Based Systems Engineering in Space Applications: A Comprehensive Literature Review

Systems Engineering, EarlyView.
ABSTRACT The growing complexity of space engineering is driving the demand to embrace the adoption of Model‐Based Systems Engineering (MBSE). Although the MBSE is well‐practiced in the space industry, the level of effort and need required to obtain the benefits of MBSE vastly differ across enterprises; this disparity presents a significant challenge to
Rehobot Bekele Buruso, Sara Himmiche, Taiwo Tejumola, Yeshirun Alemayehu, Bertrand Rose   +4 more
wiley   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

Advanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach, Reza Kowsari‐Esfahan, Emilia Reszczyńska, Philippe Nghe, Matthias Nees   +4 more
wiley   +1 more source

A user‐friendly goniometer‐compatible fixed‐target platform for macromolecular crystallography at synchrotrons

Journal of Applied Crystallography, Volume 59, Issue 2, Page 303-315, April 2026.
A user‐friendly fixed‐target platform for serial synchrotron crystallography is described, which allows low‐background X‐ray diffraction data collection, in situ crystallization and transportation of protein microcrystals at room temperature.Fixed‐target platforms provide convenient support for microcrystals during serial X‐ray crystallography studies ...
Swagatha Ghosh, Analia Banacore, Per Norder, Monica Bjelčić, Arpitha Kabbinale, Padmini Nileshwar, Gabrielle Wehlander, Daniele de Sanctis, Shibom Basu, Julien Orlans, Adams Vallejos, Leonard M. G. Chavas, Richard Neutze, Gisela Brändén   +13 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, Volume 16, Issue 1, Page 25-40, January 2026.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Organic Electrochemical Transistors Monolithically Integrated with Precise Micro‐Dispensing Enable High‐Performance Biosignals Amplification

Advanced Science, Volume 12, Issue 40, October 27, 2025.
This research showcases a micro‐dispensing strategy for integrating high‐performance organic electrochemical transistors (OECTs) and amplifiers onto flexible substrates. The method achieves precise material deposition, enabling fully micro‐dispensed OECT amplifiers with a record 1 MHz gain‐bandwidth product.
Roberto Granelli, Virginia M. Demartis, Giulia Frusconi, Zsolt M. Kovács‐Vajna, Fabrizio Torricelli   +4 more
wiley   +1 more source

A New Approach for Calculating Texture Coefficients of Different Rocks With Image Segmentation and Image Processing Techniques

Microscopy Research and Technique, Volume 88, Issue 10, Page 2612-2629, October 2025.
This study calculated the texture coefficient (TC) values of 20 different rock textures with magmatic, metamorphic, and sedimentary origins, which underwent image segmentation using a novel approach. ABSTRACT The texture coefficient (TC) is a critical parameter used to analyze the microstructural characteristics of rocks and predict their mechanical ...
Emre Karakaya, Bilgehan Kekeç, Niyazi Bilim, Fatih V. Adigözel   +3 more
wiley   +1 more source

Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells

Advanced Science, Volume 12, Issue 31, August 21, 2025.
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas, Salime Bazban‐Shotorbani, Sara Arfan, Karishma Satia, Brian Cunningham, Gauhar Sagindykova, Mymuna Ashna, Aoyu Zhang, Diana Visan, Aisher Chen, Teige Matthews‐Palmer, Mathew Carter, Fiona Blackhall, Kathryn L. Simpson, Caroline Dive, Paul Huang, Sam H. Au   +16 more
wiley   +1 more source