Results 21 to 30 of about 376 (88)

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, Volume 16, Issue 1, Page 25-40, January 2026.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Organic Electrochemical Transistors Monolithically Integrated with Precise Micro‐Dispensing Enable High‐Performance Biosignals Amplification

Advanced Science, Volume 12, Issue 40, October 27, 2025.
This research showcases a micro‐dispensing strategy for integrating high‐performance organic electrochemical transistors (OECTs) and amplifiers onto flexible substrates. The method achieves precise material deposition, enabling fully micro‐dispensed OECT amplifiers with a record 1 MHz gain‐bandwidth product.
Roberto Granelli, Virginia M. Demartis, Giulia Frusconi, Zsolt M. Kovács‐Vajna, Fabrizio Torricelli   +4 more
wiley   +1 more source

A New Approach for Calculating Texture Coefficients of Different Rocks With Image Segmentation and Image Processing Techniques

Microscopy Research and Technique, Volume 88, Issue 10, Page 2612-2629, October 2025.
This study calculated the texture coefficient (TC) values of 20 different rock textures with magmatic, metamorphic, and sedimentary origins, which underwent image segmentation using a novel approach. ABSTRACT The texture coefficient (TC) is a critical parameter used to analyze the microstructural characteristics of rocks and predict their mechanical ...
Emre Karakaya, Bilgehan Kekeç, Niyazi Bilim, Fatih V. Adigözel   +3 more
wiley   +1 more source

Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells

Advanced Science, Volume 12, Issue 31, August 21, 2025.
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas, Salime Bazban‐Shotorbani, Sara Arfan, Karishma Satia, Brian Cunningham, Gauhar Sagindykova, Mymuna Ashna, Aoyu Zhang, Diana Visan, Aisher Chen, Teige Matthews‐Palmer, Mathew Carter, Fiona Blackhall, Kathryn L. Simpson, Caroline Dive, Paul Huang, Sam H. Au   +16 more
wiley   +1 more source

Ferrofluid‐Based Bioink for 3D Printed Skeletal Muscle Tissues with Enhanced Force and Magnetic Response

Advanced Materials Interfaces, Volume 12, Issue 13, July 14, 2025.
The integration of ferrofluid consisting of citrated iron oxide nanoparticles into muscle cell‐laden ink to obtain magnetic‐responsive muscle tissue (i.e., ferromuscle) allows not only an easy printability process to integrate magnetic components in 3D printed tissues, but also impacts positively in terms of tissue differentiation and increased force ...
Judith Fuentes, Maria Guix, Zoran M. Cenev, Anna C. Bakenecker, Noelia Ruiz‐González, Grégory Beaune, Jaakko V.I. Timonen, Samuel Sanchez, Veronika Magdanz   +8 more
wiley   +1 more source

Data‐Driven Theoretical Modeling of Centrifugal Step Emulsification and Its Application in Comprehensive Multiscale Analysis

Advanced Science, Volume 12, Issue 13, April 3, 2025.
A customized assembled centrifugal step emulsifier is utilized to generate an end‐point experimental dataset for droplet generation. By integrating real‐time numerical simulations, a predictive model for droplet generation is developed, meeting the diverse droplet size requirements necessary for bioassays involving molecules, bacteria, and cells ...
Xin Wang, Xiaolu Cai, Chao Wan, Huijuan Yuan, Shunji Li, Yiwei Zhang, Ran Zhao, Yuxi Qin, Yiwei Li, Bi‐Feng Liu, Peng Chen   +10 more
wiley   +1 more source

Tumor Microenvironment On‐A‐Chip and Single‐Cell Analysis Reveal Synergistic Stromal–Immune Crosstalk on Breast Cancer Progression

Advanced Science, Volume 12, Issue 16, April 24, 2025.
Using a 3D tumor microenvironment (TME)‐on‐a‐chip model, tumor–stromal–immune crosstalk in triple‐negative breast cancer is studied, revealing the TME's combinatorial effect on cancer progression. Integrating single‐cell transcriptomic analysis demonstrates metabolic reprogramming via the kynurenine pathway, highlighting the complex TME cellular ...
Kalpana Ravi, Yining Zhang, Lydia Sakala, Twinkle Jina Minette Manoharan, Barbara Pockaj, Joshua LaBaer, Jin G. Park, Mehdi Nikkhah   +7 more
wiley   +1 more source

Mechanochemical‐Induced Swelling–Activation of a Gastric‐Deployable 4D‐Printed Polypill Inspired by Natural Hygromorphic Actuators

Advanced Intelligent Systems, Volume 7, Issue 4, April 2025.
Lifelong medication in patients with chronic diseases compromises treatment adherence, therapeutic outcomes, and quality of life. The bioinspired 4D‐printed polypill self‐deploys upon ingestion, constricting passage through the pylorus while at the same time providing sustained drug release, serving as drug delivery platform with applications in both ...
Konstantina Chachlioutaki, Nikolaos Papas, Zisis Chatzis, Orestis L. Katsamenis, Stephanie K. Robinson, Konstantinos Tsongas, Nikolaos Bouropoulos, Dimitrios G. Fatouros, Dimitrios Tzetzis, Christina Karavasili   +9 more
wiley   +1 more source

Segmented, Side‐Emitting Hydrogel Optical Fibers for Multimaterial Extrusion Printing

Advanced Materials, Volume 37, Issue 4, January 29, 2025.
Soft side‐emitting optical fibers are fabricated by multimaterial extrusion printing of hydrogel inks with contrasting optical properties. Scattering segments are distributed along waveguiding fibers and allow tailored side emission of light. The side‐emitting fibers can activate photophysical processes in a surrounding gel, showing potential for ...
Zahra Kafrashian, Stefan Brück, Peter Rogin, Mokhamad Khamdan, Hafiz Syed Usama Bin Farrukh, Samuel Pearson, Aránzazu del Campo   +6 more
wiley   +1 more source

Station Holding During Rheotaxis: A Sensitive Assay of Lateral Line Function in Larval Zebrafish. [PDF]

Bio Protoc
Cohen-Bodénès S, Malak EI, Trapani JG, Gaidica M, Militchin VA, Newton KC, Sheets L.   +6 more
europepmc   +1 more source