Results 141 to 150 of about 3,843,987 (249)

Correction to: Deep learning-based motion correction: cardiac motion artifact and image quality improvements on chest CT. [PDF]

open access: yesJpn J Radiol
Ozawa Y   +10 more
europepmc   +1 more source

Black Hills National Cemetery, 20901 Pleasant Valley Dr, Fort Meade SD, Meade County

open access: yes, 1968
4 x 5 b/w negative, American flag on a post in the center of rows of white tombstonesOrigin: Publicity Division SD Dept. of Highways PierreBlack Hills National Cemetery. Date Unknown. 2060G-102. 68-0077-
SD Department of Highways
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Tree by Bridal Veil Falls, Spearfish SD, Lawrence County

open access: yes
4 x 5 b/w negative, water cascading off a cliff onto the boulders below, a deciduous tree stands in the foregroundOrigin: Publicity Division SD Dept. of Highways PierreBridal Veil.
SD Department of Highways
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Diagnostic performance of HScore for macrophage activation syndrome complicating Still's disease in adults: a multicentre case-control study. [PDF]

open access: yesRheumatology (Oxford)
Shiga T   +11 more
europepmc   +1 more source

View of the Needles, Custer SD, Custer County

open access: yes
4 x 5 b/w negative, mountain range covered in pine treesOrigin: Publicity Division SD Dept.
SD Department of Highways
core  

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