Results 131 to 140 of about 3,843,987 (249)

Children at Roughlock Falls, Spearfish SD, Lawrence County

open access: yes, 1953
3 x 4 b/w negative, two children sitting on a boulder beneath rapids created by water cascading off the canyon wallsOrigin: Publicity Division SD Dept. of Highways PierreRoughlock Falls 2020G-103. 68-0071-
SD Department of Highways
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

People at Bridal Veil Falls, Spearfish SD, Lawrence County

open access: yes
4 x 5 b/w negative, three people watching water cascade off a cliff onto nearby bouldersOrigin: Publicity Division SD Dept. of Highways PierreBridal Veil Falls 2020G-105
SD Department of Highways
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Longer Sleep Duration Predicts Progression to Bipolar or Psychotic Disorders in Youth Accessing Early Intervention Mental Health Services. [PDF]

open access: yesBipolar Disord
Carpenter JS   +11 more
europepmc   +1 more source

House near Legion Lake, 12967 US Highway 16A, Custer SD, Custer County

open access: yes
4 x 5 b/w negative, house on the side of a hill with an automobile parked in front of a wooden barnOrigin: Publicity Division SD Dept.
SD Department of Highways
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy