Results 91 to 100 of about 29,746,039 (283)

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

SDF-1/CXCR4 Signaling Maintains Stemness Signature in Mouse Neural Stem/Progenitor Cells

Stem Cells International, 2017
SDF-1 and its primary receptor, CXCR4, are highly expressed in the embryonic central nervous system (CNS) and play a crucial role in brain architecture. Loss of SDF-1/CXCR4 signaling causes abnormal development of neural stem/progenitor cells (NSCs/NPCs)
Shih-Yin Ho, Thai-Yen Ling, Hsing-Yu Lin, Jeffrey Tsai-Jui Liou, Fei-Chih Liu, I-Chun Chen, Sue-Wei Lee, Yu Hsu, Dar-Ming Lai, Horng-Huei Liou   +9 more
doaj   +1 more source

How small changes to methylated piperidinium cations impact the synthesis of zeolite SSZ‐39

AIChE Journal, EarlyView.
Abstract Here we report a synthesis study of SSZ‐39 with four different organic structure directing agents (OSDA). The goal was to determine how subtle changes to the OSDA architecture impact crystallization kinetics, material composition, and other properties.
Onyinyechukwu Ukagha, Daniel F. Shantz
wiley   +1 more source

An unusual titanosaur axis from the Upper Cretaceous of Brazil and its significance for sauropod anatomy and systematics

The Anatomical Record, EarlyView.
Abstract The Upper Cretaceous São José do Rio Preto Formation (Bauru Group, southeastern Brazil) has yielded a fragmentary but taxonomically diverse record of titanosaur sauropods, although elements from cervical series remain scarce. Here, we describe a nearly complete sauropod axis from the Vila Ventura Paleontological Area, representing an uncommon ...
Bruno A. Navarro, Jeffrey A. Wilson Mantilla, Jhonata H. A. Martins, Fabiano V. Iori, Leonardo S. Paschoa, Alberto B. Carvalho, Joseli M. Piranha, Hussam Zaher   +7 more
wiley   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

SDF-1α and RANTES induced by MSC treatment promote migration of MSCs.

, 2018
(A) Expression of multiple chemokines in peritoneal mononuclear cells of CAIA mice treated with or without MSCs. Mononuclear cells were isolated from peritoneal wash fluid from CAIA mice. (B) In vitro scratch assay to examine MSC migration in the absence
Narae Park (4635103), Yoojun Nam (3428033), Seung Min Jung (780598), Hyerin Jung (3428042), Kijun Lee (4888660), Yeonsue Jang (3428048), Sung-Hwan Park (26633), Ji Hyeon Ju (294921), Yong-Beom Park (560297), Yeri Alice Rim (4635106), Juryun Kim (3428045)   +10 more
core   +1 more source

Biochemical Studies and Production Optimization of β‐Glucosidase From Microcystis aeruginosa CACIAM 03 Using Organic Waste

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Global warming and industrial pollutants pose significant threats to environmental sustainability. In response, enzymes have emerged as promising tools for mitigating pollution. Enzymatic hydrolysis is considered environmentally sustainable due to its biological nature.
Gustavo Marques Serra, Matheus Silva da Fonseca Diniz, Evonnildo Costa Gonçalves, Agenor Valadares Santos, Luciana Pereira Xavier   +4 more
wiley   +1 more source

Charting Water‐in‐Natural‐Salt (WiNS) Electrolytes. Part I: Effect of Anion's Alkyl Tail Length

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
At 20 m, potassium carboxylates from formate to butyrate reveal anion tail‐controlled nanostructure. SAXS shows a pre‐peak shifting to lower q with chain length. Molecular dynamics reproduces S(q) and attributes it to concentration fluctuations forming bicontinuous segregation.
Alessandra Del Giudice, Laura Hildebrandt, Jin Han, Radhika Krishna Hema, Luciano Galantini, Stefano Passerini, Alberto Varzi, Alessandro Mariani   +7 more
wiley   +1 more source

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

RETRACTED ARTICLE: MicroRNA-454 regulates stromal cell derived factor-1 in the control of the growth of pancreatic ductal adenocarcinoma

Scientific Reports, 2016
Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant carcinoma with an extremely high lethality. We recently reported that hypoxia-inducible factor 1 (HIF-1) targets quiescin sulfhydryl oxidase 1 to facilitate PDAC cell growth and invasion. Here,
Yue Fan, Li-Li Xu, Chen-Ye Shi, Wei Wei, Dan-Song Wang, Ding-Fang Cai   +5 more
doaj   +1 more source